Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR3 | P46089 | 1/20 | 0.37 |
| ▸ | PDE2A | O00408 | 2/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.33 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.33 |
| ▸ | KCNK9 | Q9NPC2 | 2/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
| ▸ | CASR | P41180 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | SYK | P43405 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13211723 | 0.86 | LMNA (0.41) | GPR3PDE2AACHEKCNK3KCNK9 | |
| SCHEMBL16961214 | 0.83 | PDE2A (0.38) | GPR3PDE2AKCNK3KCNK9HTR2A | |
| SCHEMBL16958881 | 0.83 | PDE2A (0.42) | GPR3PDE2ASCN9ASLC6A4ALDH1A1 | |
| SCHEMBL16957725 | 0.81 | CNR2 (0.35) | PDE2AHTR2ASLC6A4KCNH2APP | |
| SCHEMBL16952339 | 0.81 | HRH4 (0.39) | PDE2AKCNK3KCNK9SLC6A4APP | |
| SCHEMBL16960189 | 0.80 | CYP2D6 (0.45) | ACHEHTR2AALDH1A1ADRA1A | |
| SCHEMBL16953537 | 0.78 | GPR3 (0.41) | GPR3PDE2AACHESCN9AKCNK3 | |
| SCHEMBL16951041 | 0.78 | ACHE (0.54) | ACHEALDH1A1CYP3A4LMNAADRA1A | |
| SCHEMBL16952803 | 0.78 | HRH4 (0.42) | PDE2ASCN9ATRPA1 | |
| SCHEMBL16959252 | 0.78 | L3MBTL1 (0.40) | PDE2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |