Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | MGAM | O43451 | 1/20 | 0.37 |
| ▸ | SI | P14410 | 1/20 | 0.37 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3917312 | 0.84 | LPAR1 (0.49) | LMNALPAR1CYP2D6TDP1KDM4E | |
| SCHEMBL16960402 | 0.83 | ALDH1A1 (0.40) | LMNATDP1TSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL27885171 | 0.82 | LMNA (0.42) | LMNALPAR1CYP2D6TDP1KDM4E | |
| SCHEMBL16961368 | 0.81 | TSHR (0.47) | LMNATDP1TSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL16955354 | 0.81 | AMY1A (0.38) | LMNALPAR1TDP1KDM4ETSHR | |
| SCHEMBL23722503 | 0.81 | LMNA (0.41) | LMNALPAR1CYP2D6TDP1KDM4E | |
| SCHEMBL6278872 | 0.81 | LMNA (0.41) | LMNALPAR1CYP2D6TDP1KDM4E | |
| SCHEMBL20855486 | 0.81 | CYP2D6 (0.49) | LMNACYP2D6TDP1KDM4EADRA2A | |
| SCHEMBL7426724 | 0.81 | ADRA2A (0.45) | LMNALPAR1CYP2D6TDP1KDM4E | |
| SCHEMBL143912 | 0.81 | CYP2D6 (0.49) | LMNACYP2D6TDP1KDM4EADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |