Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 3/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 2/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 4/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TTR | P02766 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.35 |
| ▸ | VDR | P11473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12045765 | 0.86 | ALOX5 (0.47) | ALOX5CNR2CNR1SIGMAR1SMN1; SMN2 | |
| SCHEMBL15778552 | 0.84 | LMNA (0.43) | IDO1RECQLS1PR1NPC1HPGD | |
| SCHEMBL9747637 | 0.82 | CNR1 (0.41) | ALOX5CNR2CNR1LMNAGABRA1 | |
| SCHEMBL522987 | 0.81 | RECQL (0.43) | IDO1RECQLNPC1HPGDRAB9A | |
| SCHEMBL14922851 | 0.78 | BACE1 (0.42) | ALOX5CNR2CNR1LMNAVDR | |
| SCHEMBL16954455 | 0.78 | VDR (0.41) | ALOX5CNR2CNR1S1PR1VDR | |
| SCHEMBL6301168 | 0.78 | SKP2 (0.43) | SIGMAR1S1PR1NPC1HPGDRAB9A | |
| SCHEMBL16951823 | 0.77 | CNR2 (0.37) | ALOX5CNR2CNR1LMNAVDR | |
| SCHEMBL16952436 | 0.77 | CYP4F2 (0.41) | ALOX5CNR2CNR1S1PR1LMNA | |
| SCHEMBL18075992 | 0.77 | LMNA (0.41) | ALOX5CNR2CNR1SIGMAR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |