Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SKP2 | Q13309 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | IGF1R | P08069 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.41 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | TYR | P14679 | 1/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6300617 | 0.95 | ESR1 (0.46) | SIGMAR1IGF1RALOX15ALDH1A1HSD17B10 | |
| SCHEMBL6301584 | 0.84 | SKP2 (0.44) | SKP2SIGMAR1HPGDNPC1MAPK1 | |
| SCHEMBL18199330 | 0.83 | TYR (0.48) | SKP2HPGDNPC1MAPK1HTT | |
| SCHEMBL20657270 | 0.81 | TYR (0.47) | SKP2HPGDNPC1MAPK1HTT | |
| SCHEMBL8772771 | 0.81 | TRPA1 (0.43) | SIGMAR1MAPK1SMN1; SMN2LMNA | |
| SCHEMBL19000295 | 0.81 | ESR1 (0.46) | SIGMAR1IGF1RALOX15ALDH1A1HSD17B10 | |
| SCHEMBL9177318 | 0.79 | SIGMAR1 (0.62) | SKP2SIGMAR1IGF1RALOX15GLA | |
| SCHEMBL9399168 | 0.79 | ESR1 (0.47) | SIGMAR1ALDH1A1HSD17B10S1PR1ESR1 | |
| SCHEMBL522987 | 0.78 | RECQL (0.43) | HPGDNPC1MAPK1HTTRAB9A | |
| SCHEMBL574235 | 0.78 | IGF1R (0.58) | HPGDNPC1MAPK1HTTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6869950-B1 | Benzimidazole derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2005-03-22 | — | — | US | disclosed |
| EP-1142880-A1 | BENZIMIDAZOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-10-10 | — | — | EP | disclosed |