SCHEMBL1695902

SCHEMBL1695902

CCCC[Si](O[Si](C)(C)C)(O[Si](C)(C)C)O[Si](C)(C)C

nearest known ligand 0.34

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.34
ADRB2 P07550 1/20 0.33
ADRB1 P08588 1/20 0.33
ADRB3 P13945 1/20 0.33
TSHR P16473 2/20 0.32
THRB P10828 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4612835 0.92 LMNA (0.38) LMNAADRB2ADRB1ADRB3TSHR
SCHEMBL17739930 0.91 LMNA (0.31) LMNA
SCHEMBL4613469 0.90 LMNA (0.41) LMNATSHRTHRB
SCHEMBL4612616 0.90 LMNA (0.41) LMNATSHRTHRB
SCHEMBL4612788 0.90 LMNA (0.41) LMNATSHRTHRB
SCHEMBL945866 0.90 LMNA (0.41) LMNATSHRTHRB
SCHEMBL4616017 0.90 LMNA (0.41) LMNATSHRTHRB
SCHEMBL4615188 0.90 LMNA (0.41) LMNATSHRTHRB
SCHEMBL946330 0.90 LMNA (0.41) LMNATSHRTHRB
SCHEMBL4612489 0.90 LMNA (0.41) LMNATSHRTHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 74 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040197284-A1 Cosmetic composition comprising a volatile fatty phase L'OREAL S.A. (FR) 2004-10-07 US claimed
WO-2025149436-A1 W/O EMULSION COMPRISING A VOLATILE ALKANE, A NON VOLATILE MIXTURE OF C15 C19 ALKANES, AN ACYCLIC VOLATILE SILICONE OIL, A HYDROPHOBIC SILICA AEROGEL AND A SILICONE EMULSIFIER L'OREAL (FR) 2025-07-17 WO disclosed
US-20240141110-A1 POLYSILOXANE DISPERSING AGENT BYK-CHEMIE GMBH (DE) 2024-05-02 US disclosed
EP-3558222-B1 WATER-IN-OIL EMULSION COMPRISING A PARTICULAR EMULSIFYING SYSTEM, A LIPOPHILIC CLAY, AND AN ORGANOPOLYSILOXANE ELASTOMER POWDER COATED WITH A SILICONE RESIN OREAL (FR) 2024-04-03 EP disclosed
US-20240026052-A1 MONOMER COMPOSITION FOR CONTACT LENS, POLYMER FOR CONTACT LENS, AND CONTACT LENS AND METHOD FOR MANUFACTURING SAME NOF CORPORATION (JP) 2024-01-25 US disclosed
EP-4298153-A1 POLYSILOXANE DISPERSING AGENT BYK-Chemie GmbH (DE) 2024-01-03 EP disclosed
CN-116888192-A Polysiloxane dispersants 毕克化学有限公司 2023-10-13 CN disclosed
EP-3558238-B1 COMPOSITION CONTAINING AN OILY CONTINUOUS PHASE, A LIQUID DIPHENYLACRYLATE UV-SCREENING AGENT, A LIQUID SALICYLATE UV-SCREENING AGENT AND A NON-CYCLIC VOLATILE SILICONE OIL OREAL (FR) 2023-08-23 EP disclosed
WO-2022179972-A1 POLYSILOXANE DISPERSING AGENT BYK-CHEMIE GMBH (DE) 2022-09-01 WO disclosed
US-11376205-B2 Water-in-oil emulsion containing baicalin, a xanthine base, a vitamin B3, and a polyvalent metal cation salt L'OREAL (FR) 2022-07-05 US disclosed
US-7713520-B2 Cosmetic comprising a silicone polymer SHIN-ETSU CHEMICAL CO., LTD. (JP) 2010-05-11 US disclosed
US-20090074689-A1 COSMETIC COMPOSITION COMPRISING A VOLATILE FATTY PHASE L'OREAL S.A. 2009-03-19 US disclosed
US-7402689-B2 Vinylchloroformate-free synthesis of vinyl and allyl(thio) carbamates BAUSCH & LOMB INCORPORATED (US) 2008-07-22 US disclosed
EP-1481660-B1 Cosmetic SHINETSU CHEMICAL CO (JP) 2008-02-20 EP disclosed
US-20070196291-A1 Cosmetic comprising a silicone polymer SHIN-ETSU CHEMICAL CO., LTD. (JP) 2007-08-23 US disclosed
EP-1736138-A1 COSMETIC PREPARATION CONTAINING SILICONE POLYMER Shin-Etsu Chemical Company, Ltd. (JP) 2006-12-27 EP disclosed
WO-2006013413-A1 COSMETIC COMPOSITION COMPRISING A VOLATILE LINEAR ALKYLTRISILOXANE L'OREAL (FR) 2006-02-09 WO disclosed
US-20040241126-A1 Cosmetic SHIN-ETSU CHEMICAL CO., LTD. (JP) 2004-12-02 US disclosed
EP-1481660-A1 Cosmetic Shin-Etsu Chemical Co., Ltd. (JP) 2004-12-01 EP disclosed
US-20040197284-A1 Cosmetic composition comprising a volatile fatty phase L'OREAL S.A. (FR) 2004-10-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040241126-A1 Cosmetic SGMS1, ALG3, RIF1 LMNA 2493/4885ADRB2 4075/4885ADRB1 3497/4885
US-11376205-B2 Water-in-oil emulsion containing baicalin, a xanthine base, a vitamin B3, and a polyvalent metal cation salt KRT18, BROX, S100B LMNA 1468/4885ADRB2 1305/4885ADRB1 1346/4885
US-20070196291-A1 Cosmetic comprising a silicone polymer PRMT7, KAT7, SRRM2 LMNA 3432/4885ADRB2 3839/4885ADRB1 3675/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.