SCHEMBL16961007

SCHEMBL16961007

C=Cc1cc(OC(F)(F)F)ccc1OC(C)C

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TACR1 P25103 1/20 0.38
GPR3 P46089 3/20 0.37
PDE2A O00408 2/20 0.36
GRM7 Q14831 1/20 0.36
KCNK3 O14649 1/20 0.35
KCNK9 Q9NPC2 1/20 0.35
SCN10A Q9Y5Y9 1/20 0.34
IDH1 O75874 3/20 0.33
NPC1 O15118 2/20 0.33
RAB9A P51151 2/20 0.33
SLC6A2 P23975 2/20 0.33
SLC6A3 Q01959 2/20 0.33
TGM2 P21980 1/20 0.33
GMNN O75496 1/20 0.33
USP2 O75604 1/20 0.33
LMNA P02545 1/20 0.33
TP53 P04637 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP3A4 P08684 1/20 0.33
ADORA3 P0DMS8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4939627 0.85 ALDH1A3 (0.41) TACR1GPR3PDE2AGRM7KCNK3
SCHEMBL16958406 0.85 GRM7 (0.38) TACR1GPR3PDE2AGRM7KCNK3
SCHEMBL6935704 0.84 ALDH1A1 (0.41) LMNANFKB1SMN1; SMN2
SCHEMBL16953635 0.84 GPR3 (0.42) GPR3NPC1RAB9ASLC6A2SLC6A3
SCHEMBL16959108 0.83 CYP1A1 (0.44) GPR3CYP1A2NFKB1
SCHEMBL16309558 0.81 JUN (0.45) CYP1A2NFKB1BLMMAPK1
SCHEMBL16955235 0.80 TACR1 (0.39) TACR1GPR3PDE2AGRM7KCNK3
SCHEMBL16961957 0.79 S1PR1 (0.41) TACR1GPR3PDE2AGRM7LMNA
SCHEMBL16952747 0.78 PDE2A (0.43) GPR3PDE2ASCN10ANPC1RAB9A
SCHEMBL16956511 0.78 PDE2A (0.38) PDE2ASCN10ARAB9ACYP3A4RXRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2900645-A1 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION Bayer CropScience AG (DE) 2015-08-05 EP disclosed