Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | NQO1 | P15559 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.36 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.34 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.34 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | PDE2A | O00408 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 2/20 | 0.32 |
| ▸ | AHR | P35869 | 1/20 | 0.32 |
| ▸ | CCR6 | P51684 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16954164 | 0.86 | GPR3 (0.35) | MAPT | |
| SCHEMBL16955449 | 0.86 | NQO1 (0.50) | NQO1MAPTTSHRTDP1ESR1 | |
| SCHEMBL16953423 | 0.81 | TSHR (0.33) | L3MBTL1PDE2ATSHRMRGPRX4 | |
| SCHEMBL16959256 | 0.81 | L3MBTL1 (0.43) | L3MBTL1NQO1LMNAMEN1KMT2A | |
| SCHEMBL16955222 | 0.81 | ALDH1A1 (0.41) | L3MBTL1 | |
| SCHEMBL16952746 | 0.80 | RXRA (0.44) | L3MBTL1NQO1LMNAMEN1KMT2A | |
| SCHEMBL16954496 | 0.79 | ESR1 (0.50) | NQO1MAPTTSHRTDP1MAPK1 | |
| SCHEMBL21432531 | 0.79 | L3MBTL1 (0.44) | L3MBTL1NQO1LMNAMEN1KMT2A | |
| SCHEMBL16959259 | 0.79 | L3MBTL1 (0.44) | L3MBTL1NQO1LMNAMEN1KMT2A | |
| SCHEMBL16770632 | 0.77 | L3MBTL1 (0.43) | L3MBTL1NQO1LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |