SCHEMBL1696497

SCHEMBL1696497

Oc1ccc(C2COO2)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ESR2 Q92731 9/20 0.42
▸ ESR1 P03372 4/20 0.42
▸ CYP3A4 P08684 4/20 0.40
▸ CYP19A1 P11511 3/20 0.40
▸ NPC1 O15118 2/20 0.40
▸ MAPT P10636 2/20 0.40
▸ RAB9A P51151 2/20 0.40
▸ TUBB4A P04350 1/20 0.40
▸ TUBB P07437 1/20 0.40
▸ YES1 P07947 1/20 0.40
▸ TUBA3C P0DPH7 1/20 0.40
▸ TUBA1B P68363 1/20 0.40
▸ TUBA4A P68366 1/20 0.40
▸ TUBB4B P68371 1/20 0.40
▸ TUBB3 Q13509 1/20 0.40
▸ TUBB2A Q13885 1/20 0.40
▸ TUBB8 Q3ZCM7 1/20 0.40
▸ TUBA3E Q6PEY2 1/20 0.40
▸ TUBA1A Q71U36 1/20 0.40
▸ TUBA1C Q9BQE3 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2063039 0.80 TSHR (0.56) ESR2ESR1CYP3A4CYP19A1NPC1
SCHEMBL2063957 0.80 TSHR (0.56) ESR2ESR1CYP3A4CYP19A1NPC1
SCHEMBL5162162 0.75 TSHR (0.64) CYP3A4CYP19A1ADORA3MEN1KMT2A
SCHEMBL9417485 0.73 TSHR (0.61) CYP19A1ADORA3MEN1KMT2AHSD17B10
SCHEMBL29555382 0.73 TSHR (0.61) CYP19A1ADORA3MEN1KMT2AHSD17B10
Phenol SCHEMBL2208770 0.73 TSHR (0.67) ESR2CYP3A4CYP19A1NPC1MAPT
SCHEMBL29000962 0.71 ESR2 (0.50) ESR2ESR1CYP3A4CYP19A1NPC1
SCHEMBL7606736 0.69 TSHR (0.59) ESR2ESR1CYP3A4NPC1MAPT
SCHEMBL12987805 0.68 ESR2 (0.52) ESR2ESR1CYP3A4ALOX15TTR
SCHEMBL14185372 0.67 CHRM2 (0.50) ESR2CYP3A4CYP19A1NPC1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12281092-B2 Compound or salt thereof, composition, chemiluminescence method, method for measuring chemiluminescence signal, reagent, reagent kit, and method for assaying analyte SYSMEX CORPORATION (JP) 2025-04-22 — — US disclosed
US-20230242499-A1 COMPOUND OR SALT THEREOF, COMPOSITION, CHEMILUMINESCENCE METHOD, METHOD FOR MEASURING CHEMILUMINESCENCE SIGNAL, REAGENT, REAGENT KIT, AND METHOD FOR ASSAYING ANALYTE SYSMEX CORPORATION (JP) 2023-08-03 — — US disclosed
EP-4219651-A1 COMPOUND OR SALT THEREOF, COMPOSITION, CHEMILUMINESCENCE METHOD, METHOD FOR MEASURING CHEMILUMINESCENCE SIGNAL, REAGENT, REAGENT KIT, AND METHOD FOR ASSAYING ANALYTE SYSMEX CORPORATION (JP) 2023-08-02 — — EP disclosed
US-20180299456-A1 In Situ Chemiluminescent Substrates and Assays Life Technologies Corporation 2018-10-18 — — US disclosed
US-10031142-B2 In situ chemiluminescent substrates and assays Life Technologies Corporation (US) 2018-07-24 — — US disclosed
EP-2590958-B1 IN SITU CHEMILUMINESCENT SUBSTRATES AND ASSAYS LIFE TECHNOLOGIES CORP (US) 2015-08-26 — — EP disclosed
US-20140186831-A1 Solid Phases Optimized for Chemiluminescent Detection Life Technologies Corporation (US) 2014-07-03 — — US disclosed
US-20130196325-A1 In Situ Chemiluminescent Substrates and Assays Life Technologies Corporation (US) 2013-08-01 — — US disclosed
EP-2590958-A1 IN SITU CHEMILUMINESCENT SUBSTRATES AND ASSAYS Life Technologies Corporation (US) 2013-05-15 — — EP disclosed
WO-2012006351-A1 IN SITU CHEMILUMINESCENT SUBSTRATES AND ASSAYS Life Technologies Corporation (US) 2012-01-12 — — WO disclosed
EP-2163897-A1 Solid phases optimized for chemiluminescent detection Applied Biosystems, LLC (US) 2010-03-17 — — EP disclosed
EP-1470422-B8 SOLID PHASES OPTIMIZED FOR CHEMILUMINESCENT DETECTION APPLIED BIOSYSTEMS LLC (US) 2009-10-07 — — EP disclosed
EP-2101174-A1 Solid phases optimized for chemiluminescent detection Applied Biosystems, LLC (US) 2009-09-16 — — EP disclosed
EP-1470422-B1 SOLID PHASES OPTIMIZED FOR CHEMILUMINESCENT DETECTION APPLERA CORP (US) 2009-07-15 — — EP disclosed
US-20080227124-A1 Multilayer support of polylactone or polyamide and cationic polymer; bioassay; kits APPLIED BIOSYSTEMS, INC. 2008-09-18 — — US disclosed
US-7368296-B2 Multilayer support of polylactone or polyamide and cationic polymer APPLIED BIOSYSTEMS (US) 2008-05-06 — — US disclosed
EP-1470422-A4 SOLID PHASES OPTIMIZED FOR CHEMILUMINESCENT DETECTION APPLERA CORP (US) 2006-06-07 — — EP disclosed
EP-1470422-A2 SOLID PHASES OPTIMIZED FOR CHEMILUMINESCENT DETECTION Applera Corporation (US) 2004-10-27 — — EP disclosed
WO-2003062790-A2 SOLID PHASES OPTIMIZED FOR CHEMILUMINESCENT DETECTION APPLERA CORPORATION (US) 2003-07-31 — — WO disclosed
US-20030134286-A1 Multilayer support of polylactone or polyamide and cationic polymer APPLIED BIOSYSTEMS, INC. 2003-07-17 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180299456-A1 In Situ Chemiluminescent Substrates and Assays DNASE1L3, DCLRE1B, RNASE1 ESR2 2912/4885ESR1 1803/4885CYP3A4 1535/4885
US-10031142-B2 In situ chemiluminescent substrates and assays DNASE1L3, DCLRE1B, RNASE1 ESR2 2912/4885ESR1 1803/4885CYP3A4 1535/4885
US-12281092-B2 Compound or salt thereof, composition, chemiluminescence method, method for measuring chemiluminescence signal, reagent, reagent kit, and method for assaying analyte JAK2, MPO, PEAK1 ESR2 4390/4885ESR1 3411/4885CYP3A4 2373/4885
US-20230242499-A1 COMPOUND OR SALT THEREOF, COMPOSITION, CHEMILUMINESCENCE METHOD, METHOD FOR MEASURING CHEMILUMINESCENCE SIGNAL, REAGENT, REAGENT KIT, AND METHOD FOR ASSAYING ANALYTE JAK2, MPO, PEAK1 ESR2 4390/4885ESR1 3411/4885CYP3A4 2373/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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