Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOS | P01100 | 4/20 | 0.42 |
| ▸ | JUN | P05412 | 4/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 4/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 4/20 | 0.42 |
| ▸ | RELA | Q04206 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | CDC7 | O00311 | 1/20 | 0.40 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1696960 | 0.87 | EPAS1 (0.38) | SMN1; SMN2RAB9AHPGDNPC1 | |
| SCHEMBL16503738 | 0.79 | EPAS1 (0.44) | JUNNFKB1NFKB2RELA | |
| SCHEMBL16503748 | 0.79 | EPAS1 (0.41) | ALDH1A1LMNAKMT2ATSHR | |
| SCHEMBL16503753 | 0.78 | EPAS1 (0.41) | JUNNFKB1NFKB2RELAALDH1A1 | |
| SCHEMBL1696981 | 0.77 | ALDH1A1 (0.51) | ALDH1A1MAPTMAPK1ATMSMN1; SMN2 | |
| SCHEMBL16503763 | 0.76 | EPAS1 (0.37) | ALDH1A1LMNAKMT2A | |
| SCHEMBL16503751 | 0.75 | EPAS1 (0.38) | — | |
| SCHEMBL16503752 | 0.75 | SLC2A1 (0.41) | — | |
| SCHEMBL16503749 | 0.74 | EPAS1 (0.37) | RAB9AHPGDNPC1 | |
| SCHEMBL2733287 | 0.74 | ALDH1A1 (0.55) | NFKB1NFKB2RELAALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2582691-B1 | ANTHRANILIC ACID DERIVATIVES | BAYER IP GMBH (DE) | 2017-05-10 | — | — | EP | disclosed |
| EP-2533641-B1 | HYDRAZINE-SUBSTITUTED ANTHRANILIC ACID DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2016-07-13 | — | — | EP | disclosed |
| US-8980886-B2 | Anthranilic acid derivatives | BAYER CROPSCIENCE AG (DE) | 2015-03-17 | — | — | US | disclosed |
| EP-2582691-A1 | ANTHRANILIC ACID DERIVATIVES | Bayer Intellectual Property GmbH (DE) | 2013-04-24 | — | — | EP | disclosed |
| US-8410106-B2 | Hydrazine-substituted anthranilic acid derivatives | BAYER CROPSCIENCE AG (DE) | 2013-04-02 | — | — | US | disclosed |
| EP-2533641-A2 | HYDRAZINE-SUBSTITUTED ANTHRANILIC ACID DERIVATIVES | Bayer CropScience AG (DE) | 2012-12-19 | — | — | EP | disclosed |
| WO-2011157653-A1 | ANTHRANILIC ACID DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2011-12-22 | — | — | WO | disclosed |
| US-20110312953-A1 | ANTHRANILIC ACID DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2011-12-22 | — | — | US | disclosed |
| US-20110257191-A1 | Hydrazine-Substituted Anthranilic Acid Derivatives | BAYER CROPSCIENCE AG (DE) | 2011-10-20 | — | — | US | disclosed |
| WO-2011098408-A2 | HYDRAZINE-SUBSTITUTED ANTHRANILIC ACID DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2011-08-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110257191-A1 | Hydrazine-Substituted Anthranilic Acid Derivatives | ANTXR2, ACLY, H1-5 | FOS 4094/4885JUN 3875/4885NFKB1 1038/4885 |
| US-20110312953-A1 | ANTHRANILIC ACID DERIVATIVES | ANTXR2, NQO2, ACLY | FOS 3784/4885JUN 4525/4885NFKB1 351/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.