SCHEMBL1697355

SCHEMBL1697355

COc1cccc(OC(C)C)c1B(O)O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ENPP2 Q13822 1/20 0.47
ORAI1 Q96D31 1/20 0.46
ORAI2 Q96SN7 1/20 0.46
ORAI3 Q9BRQ5 1/20 0.46
CA1 P00915 4/20 0.41
CA2 P00918 4/20 0.41
CA7 P43166 3/20 0.41
CA9 Q16790 3/20 0.41
NPSR1 Q6W5P4 1/20 0.40
IRAK4 Q9NWZ3 1/20 0.40
KMT2A Q03164 1/20 0.40
ALDH1A1 P00352 2/20 0.39
TP53 P04637 2/20 0.39
KDM4E B2RXH2 1/20 0.39
LMNA P02545 1/20 0.39
CYP3A4 P08684 1/20 0.39
MAPT P10636 1/20 0.39
HPGD P15428 1/20 0.39
ALOX15 P16050 1/20 0.39
ALOX12 P18054 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29952369 1.00 ENPP2 (0.47) ENPP2ORAI1ORAI2ORAI3CA1
SCHEMBL203282 0.86 ENPP2 (0.60) ENPP2ORAI1ORAI2ORAI3CA1
SCHEMBL14982623 0.81 CA1 (0.41) ENPP2ORAI1ORAI2ORAI3CA1
SCHEMBL12538688 0.80 CA1 (0.41) CA1CA2CA7CA9NPSR1
SCHEMBL29954395 0.80 CA1 (0.41) CA1CA2CA7CA9NPSR1
Magnesium Chloride Anhydrous SCHEMBL20694977 0.79 ENPP2 (0.52) ENPP2ORAI1ORAI2ORAI3CA1
SCHEMBL12537844 0.77 ENPP2 (0.43) ENPP2ORAI1ORAI2ORAI3ALDH1A1
SCHEMBL29957347 0.77 ENPP2 (0.43) ENPP2ORAI1ORAI2ORAI3ALDH1A1
SCHEMBL16687426 0.77 CA1 (0.39) CA1CA2CA7CA9NPSR1
SCHEMBL14092740 0.75 ENPP2 (0.52) ENPP2ORAI1ORAI2ORAI3CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 125 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118390199-A Modified PBT-PET sheath-core composite fiber and preparation method thereof 江苏恒科新材料有限公司 2024-07-26 CN claimed
EP-4474446-B1 ELECTROCHROMIC COMPOUNDS, COMPOSITIONS AND DEVICES COMPRISING THE SAME ESSILOR INT (FR) 2025-12-17 EP disclosed
EP-3696602-B1 ELECTROCHROMIC ELEMENT, OPTICAL FILTER, LENS UNIT, IMAGING DEVICE, AND WINDOW MATERIAL CANON KK (JP) 2025-06-11 EP disclosed
EP-3696603-B1 ELECTROCHROMIC ELEMENT, OPTICAL FILTER, LENS UNIT, IMAGING DEVICE, AND WINDOW MATERIAL CANON KK (JP) 2025-06-04 EP disclosed
US-12174404-B2 Light-controlling device CANON KABUSHIKI KAISHA (JP) 2024-12-24 US disclosed
WO-2024251948-A1 ELECTROCHROMIC COMPOUNDS, COMPOSITIONS AND DEVICES COMPRISING THE SAME ESSILOR INTERNATIONAL (FR) 2024-12-12 WO disclosed
EP-4474446-A1 ELECTROCHROMIC COMPOUNDS, COMPOSITIONS AND DEVICES COMPRISING THE SAME Essilor International (FR) 2024-12-11 EP disclosed
US-12078905-B2 Electrochromic element, optical filter, lens unit, image pickup apparatus, and window member CANON KABUSHIKI KAISHA (JP) 2024-09-03 US disclosed
US-12081855-B2 Light modulating element and optical apparatus, imaging apparatus and lens unit using the same CANON KABUSHIKI KAISHA (JP) 2024-09-03 US disclosed
CN-118390199-A Modified PBT-PET sheath-core composite fiber and preparation method thereof 江苏恒科新材料有限公司 2024-07-26 CN disclosed
EP-2588484-A1 NOVEL ORGANIC COMPOUND AND ELECTROCHROMIC DEVICE INCLUDING THE SAME Canon Kabushiki Kaisha (JP) 2013-05-08 EP disclosed
US-20130100517-A1 NOVEL ORGANIC COMPOUND AND ELECTROCHROMIC DEVICE INCLUDING THE SAME CANON KABUSHIKI KAISHA (JP) 2013-04-25 US disclosed
US-20130100517-A1 NOVEL ORGANIC COMPOUND AND ELECTROCHROMIC DEVICE INCLUDING THE SAME CANON KABUSHIKI KAISHA (JP) 2013-04-25 US disclosed
US-20130100517-A1 NOVEL ORGANIC COMPOUND AND ELECTROCHROMIC DEVICE INCLUDING THE SAME CANON KABUSHIKI KAISHA (JP) 2013-04-25 US disclosed
US-20120314272-A1 ELECTROCHROMIC DEVICE CANON KABUSHIKI KAISHA (JP) 2012-12-13 US disclosed
US-20120314272-A1 ELECTROCHROMIC DEVICE CANON KABUSHIKI KAISHA (JP) 2012-12-13 US disclosed
US-20120314272-A1 ELECTROCHROMIC DEVICE CANON KABUSHIKI KAISHA (JP) 2012-12-13 US disclosed
US-20120245124-A1 TRPV3 Modulators ABBOTT LABORATORIES (US) 2012-09-27 US disclosed
WO-2012129491-A1 TRPV3 MODULATORS ABBOTT LABORATORIES (US) 2012-09-27 WO disclosed
WO-2012002185-A1 NOVEL ORGANIC COMPOUND AND ELECTROCHROMIC DEVICE INCLUDING THE SAME CANON KABUSHIKI KAISHA (JP) 2012-01-05 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120245124-A1 TRPV3 Modulators TRPV3, TRPV2, TRPV1 ENPP2 353/4885ORAI1 42/4885ORAI2 96/4885
US-20130100517-A1 NOVEL ORGANIC COMPOUND AND ELECTROCHROMIC DEVICE INCLUDING THE SAME CCNL2, DNMT3L, ARL1 ENPP2 2930/4885ORAI1 1082/4885ORAI2 136/4885
US-12078905-B2 Electrochromic element, optical filter, lens unit, image pickup apparatus, and window member HCN2, HCN4, HCN3 ENPP2 1372/4885ORAI1 27/4885ORAI2 34/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.