Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.42 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.42 |
| ▸ | ORAI2 | Q96SN7 | 1/20 | 0.42 |
| ▸ | ORAI3 | Q9BRQ5 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | FPR2 | P25090 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12537844 | 1.00 | ENPP2 (0.43) | ENPP2LMNACYP1A2AGTR1ORAI1 | |
| SCHEMBL203282 | 0.82 | ENPP2 (0.60) | ENPP2LMNAORAI1ORAI2ORAI3 | |
| SCHEMBL17236435 | 0.81 | NFKB1 (0.38) | LMNACYP1A2AGTR1HTR2CSMN1; SMN2 | |
| SCHEMBL16687430 | 0.80 | ALDH1A1 (0.42) | LMNAHTR2CSMN1; SMN2ALDH1A1GAA | |
| SCHEMBL5787704 | 0.79 | ENPP2 (0.46) | ENPP2LMNAAGTR1ORAI1ORAI2 | |
| SCHEMBL29952369 | 0.77 | ENPP2 (0.47) | ENPP2LMNAORAI1ORAI2ORAI3 | |
| SCHEMBL1697355 | 0.77 | ENPP2 (0.47) | ENPP2LMNAORAI1ORAI2ORAI3 | |
| SCHEMBL1446334 | 0.76 | LMNA (0.61) | LMNACYP1A2AGTR1HTR2CSMN1; SMN2 | |
| SCHEMBL15475933 | 0.75 | LIPE (0.63) | ENPP2SMN1; SMN2MAPTHPGDMAPK1 | |
| SCHEMBL22114346 | 0.75 | SMN1; SMN2 (0.52) | LMNACYP1A2AGTR1SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |