Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1573387 | 0.81 | TDP1 (0.45) | ALDH1A1TSHRACHETDP1MEN1 | |
| SCHEMBL7185336 | 0.81 | SLC6A2 (0.36) | — | |
| SCHEMBL301933 | 0.78 | ALDH1A1 (0.69) | ALDH1A1TSHRHPGDHTTAR | |
| Ammonia Solution, Strong SCHEMBL10338964 | 0.76 | ALDH1A1 (0.67) | ALDH1A1TSHRHPGDHTTAR | |
| SCHEMBL10651374 | 0.72 | ALDH1A1 (0.56) | ALDH1A1TSHRHPGDHTTAR | |
| SCHEMBL6912491 | 0.71 | GABRA1 (0.40) | TSHRL3MBTL1TDP1POLB | |
| SCHEMBL6280650 | 0.71 | CNR2 (0.44) | ALDH1A1TSHRL3MBTL1SIGMAR1TDP1 | |
| SCHEMBL7189957 | 0.70 | SLC6A2 (0.36) | — | |
| SCHEMBL28369479 | 0.69 | TDP1 (0.42) | ALDH1A1TSHRACHETDP1MEN1 | |
| SCHEMBL13777208 | 0.68 | HSD17B10 (0.62) | ALDH1A1TSHRHPGDHTTAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011144983-A2 | AN IMPROVED PROCESS FOR THE PREPARATION OF LACOSAMIDE | AUROBINDO PHARMA LIMITED (IN) | 2011-11-24 | — | — | WO | disclosed |