Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 2/20 | 0.44 |
| ▸ | IDO1 | P14902 | 3/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7185336 | 0.83 | SLC6A2 (0.36) | SLC6A2HTR2ASLC6A4HRH1OPRD1 | |
| SCHEMBL8766176 | 0.80 | SLC6A2 (0.43) | CHRM2CHRM1ALDH1A1MAPTLMNA | |
| SCHEMBL3296809 | 0.76 | IDO1 (0.61) | CNR2IDO1TAAR1SIGMAR1CHRM2 | |
| SCHEMBL18872489 | 0.76 | HTR2B (0.38) | ADRA1ASLC6A2HTR2ASLC6A4HRH1 | |
| SCHEMBL6912491 | 0.73 | GABRA1 (0.40) | TAAR1MAPTL3MBTL1LMNATSHR | |
| SCHEMBL7189957 | 0.73 | SLC6A2 (0.36) | SLC6A2HTR2ASLC6A4HRH1OPRD1 | |
| SCHEMBL22800045 | 0.71 | IDO1 (0.52) | CNR2IDO1TAAR1SIGMAR1CHRM2 | |
| SCHEMBL4751824 | 0.71 | LMNA (0.54) | CNR2HRH3LMNA | |
| SCHEMBL1697397 | 0.71 | ALDH1A1 (0.45) | SIGMAR1ALDH1A1L3MBTL1TSHRTDP1 | |
| SCHEMBL6912026 | 0.70 | HTR2A (0.34) | CHRM2KCNH2HRH3LMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005044279-A1 | PURINE NUCLEOSIDE PHOSPHONATE CONJUGATES | GILEAD SCIENCES, INC. (US) | 2005-05-19 | — | — | WO | disclosed |