SCHEMBL1697979

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2439449	0.93	TRPA1 (0.41)	TRPA1KDM4EATMKMT2AMEN1
	SCHEMBL14825959	0.79	TRPA1 (0.61)	TRPA1KDM4EATMKMT2AMEN1
	SCHEMBL10036427	0.79	TRPA1 (0.61)	TRPA1KDM4EATMKMT2AMEN1
	SCHEMBL14826007	0.79	TRPA1 (0.61)	TRPA1KDM4EATMKMT2AMEN1
	SCHEMBL19287161	0.78	HIF1A (0.38)	MAPTTRPV1
	SCHEMBL14322226	0.74	KDM4E (0.50)	KDM4EATMKMT2AALOX15POLB
	SCHEMBL13307729	0.74	FNTA (0.46)	KDM4EATMKMT2AALOX15POLB
	SCHEMBL13259644	0.73	ALDH1A1 (0.41)	TRPA1KDM4EPOLBMAPTALDH1A1
	SCHEMBL12032341	0.73	FNTA (0.58)	ATMKMT2AALOX15POLBMAPT
	SCHEMBL6141447	0.73	CES2 (0.50)	KMT2AMEN1ALOX15ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.