SCHEMBL1697993

SCHEMBL1697993

Cc1ccccc1CC(C)(C)C(C)(C)O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 1/20 0.42
SSTR4 P31391 1/20 0.40
NR3C2 P08235 1/20 0.40
NR3C1 P04150 1/20 0.39
HPGD P15428 2/20 0.37
ALDH1A1 P00352 2/20 0.37
CTBP2 P56545 1/20 0.37
ADRB2 P07550 1/20 0.37
ADRB1 P08588 1/20 0.37
GABRA1 P14867 1/20 0.36
GABRB2 P47870 1/20 0.36
CHRM2 P08172 1/20 0.36
PTGS1 P23219 1/20 0.36
PTGS2 P35354 1/20 0.36
TSHR P16473 2/20 0.36
ACHE P22303 1/20 0.36
MAPT P10636 1/20 0.36
LMNA P02545 1/20 0.36
KMT2A Q03164 1/20 0.35
SLC6A2 P23975 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15976426 0.83 TAAR1 (0.45) TAAR1SSTR4NR3C2NR3C1HPGD
SCHEMBL13722854 0.83 TAAR1 (0.45) TAAR1SSTR4NR3C2NR3C1HPGD
SCHEMBL808983 0.83 TAAR1 (0.45) TAAR1SSTR4NR3C2NR3C1HPGD
SCHEMBL19085950 0.83 TAAR1 (0.45) TAAR1SSTR4NR3C2NR3C1HPGD
SCHEMBL24848861 0.79 TAAR1 (0.42) TAAR1SSTR4NR3C2NR3C1HPGD
SCHEMBL3167835 0.78 RIPK1 (0.48) TAAR1SSTR4NR3C2NR3C1HPGD
SCHEMBL14142999 0.76 TAAR1 (0.39) TAAR1SSTR4NR3C2NR3C1HPGD
SCHEMBL2958719 0.75 TAAR1 (0.42) TAAR1SSTR4NR3C2NR3C1HPGD
SCHEMBL3638610 0.74 TAAR1 (0.52) TAAR1SSTR4NR3C2ALDH1A1ADRB2
SCHEMBL29987056 0.74 TAAR1 (0.52) TAAR1SSTR4NR3C2ALDH1A1ADRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2585569-A1 PERFUME SYSTEMS The Procter and Gamble Company (US) 2013-05-01 EP claimed
WO-2011163337-A1 PERFUME SYSTEMS THE PROCTER & GAMBLE COMPANY (US) 2011-12-29 WO claimed
US-20110308555-A1 PERFUME SYSTEMS PROCTER & GAMBLE COMPANY, THE 2011-12-22 US claimed
EP-3085759-B1 PERFUME SYSTEMS PROCTER & GAMBLE (US) 2018-02-07 EP disclosed
EP-3085759-B1 PERFUME SYSTEMS PROCTER & GAMBLE (US) 2018-02-07 EP disclosed
EP-3085759-A2 PERFUME SYSTEMS The Procter and Gamble Company (US) 2016-10-26 EP disclosed
EP-3085759-A2 PERFUME SYSTEMS The Procter and Gamble Company (US) 2016-10-26 EP disclosed
EP-2585569-B1 PERFUME SYSTEMS PROCTER & GAMBLE (US) 2016-08-24 EP disclosed
US-8609603-B2 Perfume systems THE PROCTER & GAMBLE COMPANY (US) 2013-12-17 US disclosed
EP-2585569-A1 PERFUME SYSTEMS The Procter and Gamble Company (US) 2013-05-01 EP disclosed
US-20110308555-A1 PERFUME SYSTEMS PROCTER & GAMBLE COMPANY, THE 2011-12-22 US disclosed
US-20110308555-A1 PERFUME SYSTEMS PROCTER & GAMBLE COMPANY, THE 2011-12-22 US disclosed
US-20110308555-A1 PERFUME SYSTEMS PROCTER & GAMBLE COMPANY, THE 2011-12-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110308555-A1 PERFUME SYSTEMS TRPA1, PORCN, PLIN5 TAAR1 615/4885SSTR4 2383/4885NR3C2 4575/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.