Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | LTA4H | P09960 | 1/20 | 0.34 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.33 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.33 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17030789 | 0.86 | PDE3B (0.40) | ALDH1A1HTTLTA4HMTNR1AMTNR1B | |
| SCHEMBL14013331 | 0.84 | LTA4H (0.40) | ALDH1A1HTTLTA4HMTNR1AMTNR1B | |
| SCHEMBL16985198 | 0.80 | ALDH1A1 (0.41) | ALDH1A1HTTLTA4HCRHR1MTNR1A | |
| SCHEMBL4275474 | 0.75 | TSHR (0.43) | ALDH1A1HTTLTA4HMAPTLMNA | |
| SCHEMBL16985197 | 0.72 | TSHR (0.45) | ALDH1A1HTTCRHR1MAPTLMNA | |
| SCHEMBL14038445 | 0.72 | THRA (0.47) | ALDH1A1LTA4HMAPTKMT2APDE3B | |
| SCHEMBL2502826 | 0.71 | TSHR (0.44) | ALDH1A1HTTMAPTLMNAKMT2A | |
| SCHEMBL22693005 | 0.70 | KMT2A (0.34) | ALDH1A1CRHR1MTNR1AMTNR1BMAPT | |
| SCHEMBL27396405 | 0.69 | ALDH1A1 (0.41) | ALDH1A1MAPTKMT2ATDP1 | |
| SCHEMBL16986038 | 0.69 | HSP90AA1 (0.35) | HTTCRHR1MAPTTAS1R3TAS1R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9599622-B2 | Fluorogenic pH-sensitive dyes and their methods of use (II) | Life Technologies Corporation (US) | 2017-03-21 | — | — | US | disclosed |
| US-20150218379-A1 | Fluorogenic pH-Sensitive Dyes and Their Methods of Use (II) | Life Technologies Corporation | 2015-08-06 | — | — | US | disclosed |