Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.40 |
| ▸ | HPGD | P15428 | 6/20 | 0.40 |
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.39 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16985198 | 0.91 | ALDH1A1 (0.41) | PPARGALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL2502826 | 0.89 | TSHR (0.44) | TSHRPPARGALDH1A1HPGDGAA | |
| SCHEMBL4275474 | 0.88 | TSHR (0.43) | TSHRPPARGALDH1A1HPGDNPC1 | |
| SCHEMBL2502597 | 0.86 | NLRP3 (0.43) | TSHRALDH1A1HPGDALOX5MEN1 | |
| SCHEMBL2502591 | 0.80 | MTNR1A (0.52) | TSHRPPARGALDH1A1MEN1KMT2A | |
| SCHEMBL17030789 | 0.80 | PDE3B (0.40) | ALDH1A1GAAKMT2AKDM4ELMNA | |
| SCHEMBL11310244 | 0.78 | CRHR1 (0.42) | TSHRALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL14013331 | 0.78 | LTA4H (0.40) | ALDH1A1NPC1RAB9AKMT2AKDM4E | |
| SCHEMBL14163399 | 0.76 | TNF (0.39) | ALDH1A1ALOX5MEN1KMT2AKDM4E | |
| SCHEMBL12061824 | 0.75 | ALOX5 (0.40) | ALDH1A1ALOX5MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170145214-A1 | FLUOROGENIC PH-SENSITIVE DYES AND THEIR METHODS OF USE (II) | Life Technologies Corporation | 2017-05-25 | — | — | US | disclosed |
| US-9599622-B2 | Fluorogenic pH-sensitive dyes and their methods of use (II) | Life Technologies Corporation (US) | 2017-03-21 | — | — | US | disclosed |
| US-20150241438-A1 | Fluorogenic pH-Sensitive Dyes and Their Methods of Use | Life Technologies Corporation | 2015-08-27 | — | — | US | disclosed |
| US-20150218379-A1 | Fluorogenic pH-Sensitive Dyes and Their Methods of Use (II) | Life Technologies Corporation | 2015-08-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150241438-A1 | Fluorogenic pH-Sensitive Dyes and Their Methods of Use | ALPG, XDH, HEXD | TSHR 4478/4885PPARG 4206/4885ALDH1A1 960/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.