Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 5/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16985197 | 0.91 | TSHR (0.45) | ALDH1A1CRHR1HTTLMNAMAPT | |
| SCHEMBL17030789 | 0.88 | PDE3B (0.40) | ALDH1A1HTTLMNAMAPTHSD17B10 | |
| SCHEMBL14013331 | 0.86 | LTA4H (0.40) | ALDH1A1HTTLMNAMAPTHSD17B10 | |
| SCHEMBL16986013 | 0.80 | ALDH1A1 (0.34) | ALDH1A1CRHR1HTTLMNAMAPT | |
| SCHEMBL2502826 | 0.80 | TSHR (0.44) | ALDH1A1HTTLMNAMAPTSMN1; SMN2 | |
| SCHEMBL4275474 | 0.79 | TSHR (0.43) | ALDH1A1HTTLMNAMAPTKMT2A | |
| SCHEMBL11310244 | 0.79 | CRHR1 (0.42) | ALDH1A1CRHR1HTTLMNAMAPT | |
| SCHEMBL14038445 | 0.78 | THRA (0.47) | ALDH1A1MAPTKMT2AMEN1LTA4H | |
| SCHEMBL14882515 | 0.77 | TDP1 (0.43) | ALDH1A1HTTMAPTHSD17B10KMT2A | |
| SCHEMBL2502597 | 0.76 | NLRP3 (0.43) | ALDH1A1MAPTHSD17B10SMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170145214-A1 | FLUOROGENIC PH-SENSITIVE DYES AND THEIR METHODS OF USE (II) | Life Technologies Corporation | 2017-05-25 | — | — | US | disclosed |
| US-9599622-B2 | Fluorogenic pH-sensitive dyes and their methods of use (II) | Life Technologies Corporation (US) | 2017-03-21 | — | — | US | disclosed |
| US-20150241438-A1 | Fluorogenic pH-Sensitive Dyes and Their Methods of Use | Life Technologies Corporation | 2015-08-27 | — | — | US | disclosed |
| US-20150218379-A1 | Fluorogenic pH-Sensitive Dyes and Their Methods of Use (II) | Life Technologies Corporation | 2015-08-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150241438-A1 | Fluorogenic pH-Sensitive Dyes and Their Methods of Use | ALPG, XDH, HEXD | ALDH1A1 960/4885CRHR1 4463/4885HTT 2849/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.