Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 15/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | POLQ | O75417 | 1/20 | 0.32 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.31 |
| ▸ | TACR2 | P21452 | 1/20 | 0.31 |
| ▸ | TACR1 | P25103 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16986375 | 0.94 | GPBAR1 (0.36) | GPBAR1HDAC8NR1H3 | |
| SCHEMBL16986370 | 0.90 | GPBAR1 (0.34) | GPBAR1HDAC8 | |
| SCHEMBL16986339 | 0.89 | GPBAR1 (0.34) | GPBAR1HDAC8POLQNR1H3TACR2 | |
| SCHEMBL16986325 | 0.88 | RORC (0.35) | GPBAR1HDAC8 | |
| SCHEMBL12348556 | 0.87 | GPBAR1 (0.38) | GPBAR1HDAC8NR1H3 | |
| SCHEMBL28992868 | 0.86 | GPBAR1 (0.36) | GPBAR1HDAC8NR1H3 | |
| SCHEMBL16986310 | 0.85 | NR1H3 (0.38) | GPBAR1HDAC8POLQNR1H3 | |
| SCHEMBL29427435 | 0.84 | HDAC8 (0.35) | GPBAR1HDAC8TACR2TACR1 | |
| SCHEMBL1766772 | 0.84 | HDAC8 (0.35) | GPBAR1HDAC8TACR2TACR1 | |
| SCHEMBL16986302 | 0.83 | NR1H3 (0.38) | GPBAR1HDAC8NR1H3TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3392236-B1 | METHOD FOR PRODUCING AROMATIC AMIDE DERIVATIVE | MITSUI CHEMICALS AGRO INC (JP) | 2021-06-23 | — | — | EP | disclosed |
| US-10647660-B2 | Method of producing aromatic amide derivative | MITSUI CHEMICALS AGRO, INC. (JP) | 2020-05-12 | — | — | US | disclosed |
| EP-2905274-B1 | IMIDE COMPOUND, METHOD FOR MANUFACTURING SAME, AND USE AS INSECTICIDE | MITSUI CHEMICALS AGRO INC (JP) | 2019-09-25 | — | — | EP | disclosed |
| US-20180362447-A1 | METHOD OF PRODUCING AROMATIC AMIDE DERIVATIVE | MITSUI CHEMICALS AGRO, INC. (JP) | 2018-12-20 | — | — | US | disclosed |
| EP-3392236-A1 | METHOD FOR PRODUCING AROMATIC AMIDE DERIVATIVE | Mitsui Chemicals Agro, Inc. (JP) | 2018-10-24 | — | — | EP | disclosed |
| US-9328062-B2 | Imide compound, method for manufacturing same, and use as insecticide | MITSUI CHEMICALS AGRO, INC. (JP) | 2016-05-03 | — | — | US | disclosed |
| US-20150246872-A1 | IMIDE COMPOUND, METHOD FOR MANUFACTURING SAME, AND USE AS INSECTICIDE | MITSUI CHEMICALS AGRO, INC. (JP) | 2015-09-03 | — | — | US | disclosed |
| EP-2905274-A1 | IMIDE COMPOUND, METHOD FOR MANUFACTURING SAME, AND USE AS INSECTICIDE | Mitsui Chemicals Agro, Inc. (JP) | 2015-08-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150246872-A1 | IMIDE COMPOUND, METHOD FOR MANUFACTURING SAME, AND USE AS INSECTICIDE | CYP2E1, CYP1A1, CYP4B1 | GPBAR1 4463/4885HDAC8 3488/4885POLQ 3054/4885 |
| US-20180362447-A1 | METHOD OF PRODUCING AROMATIC AMIDE DERIVATIVE | HDHD5, NAAA, H1-4 | GPBAR1 4388/4885HDAC8 1517/4885POLQ 684/4885 |
| US-10647660-B2 | Method of producing aromatic amide derivative | HDHD5, NAAA, H1-4 | GPBAR1 4388/4885HDAC8 1517/4885POLQ 684/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.