Sugi Predict

Sugi Predict / Compounds / SCHEMBL1766772

SCHEMBL1766772

SCHEMBL1766772

CN(C(=O)c1ccc(F)cc1)c1cccc(C(=O)Nc2c(Br)cc(C(F)(C(F)(F)F)C(F)(F)F)cc2C(F)(F)F)c1F

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ HDAC8 Q9BY41 1/20 0.35
▸ GPBAR1 Q8TDU6 3/20 0.34
▸ MAPT P10636 3/20 0.34
▸ NPSR1 Q6W5P4 2/20 0.34
▸ XBP1 P17861 1/20 0.34
▸ KDM4E B2RXH2 1/20 0.34
▸ TACR1 P25103 2/20 0.34
▸ TACR2 P21452 1/20 0.34
▸ MEN1 O00255 3/20 0.33
▸ KMT2A Q03164 3/20 0.33
▸ BCHE P06276 1/20 0.33
▸ CA12 O43570 1/20 0.33
▸ CA9 Q16790 1/20 0.33
▸ RXFP1 Q9HBX9 1/20 0.33
▸ NPC1 O15118 1/20 0.33
▸ HTT P42858 1/20 0.33
▸ RAB9A P51151 1/20 0.33
▸ SMN1; SMN2 Q16637 2/20 0.33
▸ LMNA P02545 1/20 0.32
▸ PTGES O14684 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29427435 1.00 HDAC8 (0.35) HDAC8GPBAR1MAPTNPSR1XBP1
SCHEMBL20846939 0.96 GPBAR1 (0.33) HDAC8GPBAR1MAPTNPSR1XBP1
SCHEMBL29733643 0.94 MEN1 (0.39) HDAC8GPBAR1MAPTMEN1KMT2A
SCHEMBL29427851 0.94 MEN1 (0.39) HDAC8GPBAR1MAPTMEN1KMT2A
SCHEMBL1766891 0.94 MEN1 (0.39) HDAC8GPBAR1MAPTMEN1KMT2A
SCHEMBL29361693 0.94 MEN1 (0.39) HDAC8GPBAR1MAPTMEN1KMT2A
SCHEMBL1767229 0.94 KDM4E (0.36) GPBAR1MAPTKDM4ETACR1TACR2
SCHEMBL1766386 0.92 KCNJ11 (0.35) HDAC8GPBAR1MAPTMEN1KMT2A
SCHEMBL1766850 0.91 GPBAR1 (0.38) GPBAR1RXFP1
SCHEMBL19334943 0.91 KDM4E (0.39) HDAC8GPBAR1KDM4ETACR1TACR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 353 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240225002-A1 FUNGICIDAL COMPOSITION CONTAINING OXADIAZOLE COMPOUNDS PI INDUSTRIES LTD. (IN) 2024-07-11 — — US claimed
EP-4346412-A1 FUNGICIDAL COMPOSITION CONTAINING OXADIAZOLE COMPOUNDS PI Industries Ltd. (IN) 2024-04-10 — — EP claimed
CN-117396074-A Fungicidal compositions containing oxadiazole compounds PI工业有限公司 2024-01-12 — — CN claimed
US-11839214-B2 Fungicidal mixture comprising substituted pyridines BASF SE (DE) 2023-12-12 — — US claimed
CN-116076518-A Pyrimidinium compounds and mixtures thereof for combating animal pests 巴斯夫欧洲公司 2023-05-09 — — CN claimed
EP-3601298-B1 PROCESS FOR PREPARING CHIRAL 2,3-DIHYDROTHIAZOLO[3,2-A]PYRIMIDIN-4-IUM COMPOUNDS BASF SE (DE) 2021-12-01 — — EP claimed
US-20210355139-A1 Pyrimidinium Compounds and Their Mixtures for Combating Animal Pests BASF SE (DE) 2021-11-18 — — US claimed
CN-113303339-A Mixture of cis-jasmone and bacillus amyloliquefaciens 巴斯夫欧洲公司 2021-08-27 — — CN claimed
EP-3057419-B1 AGRICULTURAL MIXTURES COMPRISING CARBOXAMIDE COMPOUND BASF AGROCHEMICAL PRODUCTS BV (NL) 2021-07-28 — — EP claimed
US-20210084902-A1 FUNGICIDAL MIXTURE COMPRISING SUBSTITUTED 3-PHENYL-5-(TRIFLUOROMETHYL)-1,2,4-OXADIAZOLES BASF SE (DE) 2021-03-25 — — US claimed
EP-3057419-A1 AGRICULTURAL MIXTURES COMPRISING CARBOXAMIDE COMPOUND BASF Agrochemical Products B.V. (NL) 2016-08-24 — — EP claimed
EP-3057420-A1 USE OF PESTICIDAL ACTIVE CARBOXAMIDE DERIVATIVE IN SOIL AND SEED APPLICATION AND TREATMENT METHODS BASF Agrochemical Products B.V. (NL) 2016-08-24 — — EP claimed
WO-2016128261-A2 PESTICIDAL MIXTURE COMPRISING A PYRAZOLE COMPOUND, AN INSECTICIDE AND A FUNGICIDE BASF SE (DE) 2016-08-18 — — WO claimed
US-20160227772-A1 AGRICULTURAL MIXTURES COMPRISING CARBOXAMIDE COMPOUND BASF AGROCHEMICAL PRODUCTS B.V. (NL) 2016-08-11 — — US claimed
US-20160227771-A1 Insecticidal Active Mixtures Comprising Carboxamide Compound BASF AGROCHEMICAL PRODUCTS B.V. (NL) 2016-08-11 — — US claimed
WO-2016079043-A1 PESTICIDAL COMPOSITIONS COMPRISING A TRIAZOLE COMPOUND BASF Agro B.V. (NL) 2016-05-26 — — WO claimed
WO-2016059240-A1 METHOD AND PESTICIDAL MIXTURES FOR CONTROLLING PENTATOMIDAE PESTS BASF SE (DE) 2016-04-21 — — WO claimed
WO-2015055755-A1 AGRICULTURAL MIXTURES COMPRISING CARBOXAMIDE COMPOUND BASF SE (DE) 2015-04-23 — — WO claimed
WO-2015055757-A1 USE OF PESTICIDAL ACTIVE CARBOXAMIDE DERIVATIVE IN SOIL AND SEED APPLICATION AND TREATMENT METHODS BASF SE (DE) 2015-04-23 — — WO claimed
WO-2015055752-A1 INSECTICIDAL ACTIVE MIXTURES COMPRISING CARBOXAMIDE COMPOUND BASF SE (DE) 2015-04-23 — — WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11839214-B2 Fungicidal mixture comprising substituted pyridines ME1, DPM1, TH HDAC8 2641/4885GPBAR1 3883/4885MAPT 1386/4885
US-20160227772-A1 AGRICULTURAL MIXTURES COMPRISING CARBOXAMIDE COMPOUND NAAA, AADAC, PYCARD HDAC8 349/4885GPBAR1 4592/4885MAPT 2709/4885
US-20210084902-A1 FUNGICIDAL MIXTURE COMPRISING SUBSTITUTED 3-PHENYL-5-(TRIFLUOROMETHYL)-1,2,4-OXADIAZOLES TH, CASP3, PIK3C3 HDAC8 1943/4885GPBAR1 3796/4885MAPT 2168/4885
US-20160227771-A1 Insecticidal Active Mixtures Comprising Carboxamide Compound ATP5ME, MT-ATP6, ATP5MG HDAC8 2084/4885GPBAR1 1955/4885MAPT 3497/4885
US-20240225002-A1 FUNGICIDAL COMPOSITION CONTAINING OXADIAZOLE COMPOUNDS OXA1L, NOX1, NOX3 HDAC8 3231/4885GPBAR1 3199/4885MAPT 3601/4885
US-20210355139-A1 Pyrimidinium Compounds and Their Mixtures for Combating Animal Pests THOP1, NIT2, DDT HDAC8 4819/4885GPBAR1 1589/4885MAPT 1118/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.