SCHEMBL1699351

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1701440	0.83	ALDH1A1 (0.42)	LMNAKMT2AMEN1ALDH1A1MAPT
	SCHEMBL15165286	0.82	MAPT (0.39)	LMNAKMT2AMEN1ALDH1A1MAPT
	SCHEMBL1699400	0.82	KDM4E (0.41)	LMNAALDH1A1NPC1MAPTRAB9A
	SCHEMBL1699649	0.80	PTGDR2 (0.43)	LMNAALDH1A1MAPTSMN1; SMN2TP53
	SCHEMBL1699415	0.77	PTGDR2 (0.41)	LMNAPLA2G2AALDH1A1MAPTSMN1; SMN2
	SCHEMBL15165189	0.75	CYP3A4 (0.41)	KMT2APLA2G2APTGDR2MAP2FABP3
	SCHEMBL1699452	0.75	CYP3A4 (0.50)	PLA2G2APTGDR2FABP3FABP4
	SCHEMBL15334224	0.74	SMN1; SMN2 (0.43)	KMT2AMEN1TACR3ALDH1A1NPC1
	SCHEMBL15334221	0.74	SMN1; SMN2 (0.43)	KMT2AMEN1TACR3ALDH1A1NPC1
	SCHEMBL10272102	0.74	PTGDR2 (0.37)	LMNAKMT2AMEN1ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.