SCHEMBL1701440

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL15165286	0.92	MAPT (0.39)	ALDH1A1MAPTLMNATDP1TP53
	SCHEMBL1699400	0.89	KDM4E (0.41)	ALDH1A1MAPTLMNATDP1HPGD
	SCHEMBL1699649	0.87	PTGDR2 (0.43)	ALDH1A1MAPTLMNATDP1TP53
	SCHEMBL1699351	0.83	LMNA (0.38)	ALDH1A1MAPTLMNATP53MDM2
	SCHEMBL15099648	0.83	HTT (0.39)	ALDH1A1MAPTLMNATDP1TP53
	SCHEMBL1699639	0.83	HTT (0.39)	ALDH1A1MAPTLMNATDP1TP53
	SCHEMBL10272102	0.83	PTGDR2 (0.37)	ALDH1A1MAPTLMNATDP1HPGD
	SCHEMBL15165288	0.79	GCGR (0.39)	ALDH1A1MAPTLMNATDP1HPGD
	SCHEMBL1699420	0.78	MTNR1B (0.38)	ALDH1A1MAPTLMNATDP1TP53
	SCHEMBL1701370	0.78	CSF1R (0.41)	ALDH1A1MAPTLMNATDP1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.