SCHEMBL1699649

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL15099648	0.91	HTT (0.39)	PTGDR2ALDH1A1HPGDLMNAMAPT
	SCHEMBL1699639	0.91	HTT (0.39)	PTGDR2ALDH1A1HPGDLMNAMAPT
	SCHEMBL1701440	0.87	ALDH1A1 (0.42)	ALDH1A1HPGDCYP1A2XBP1CYP2C19
	SCHEMBL15165286	0.86	MAPT (0.39)	ALDH1A1HPGDCYP1A2XBP1CYP2C19
	SCHEMBL1699653	0.85	ALOX15 (0.41)	ALDH1A1HPGDCYP1A2XBP1CYP2C19
	SCHEMBL1699400	0.83	KDM4E (0.41)	ALDH1A1HPGDLMNAMAPTTDP1
	SCHEMBL1699594	0.83	PTGDR2 (0.40)	PTGDR2ALDH1A1HPGDCYP1A2XBP1
	SCHEMBL1699351	0.80	LMNA (0.38)	PTGDR2ALDH1A1LMNAMAPTCSF1R
	SCHEMBL1699420	0.79	MTNR1B (0.38)	ALDH1A1HPGDCYP1A2XBP1CYP2C19
	SCHEMBL1701854	0.79	ALOX15 (0.39)	ALDH1A1LMNAMAPTALOX15TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.