SCHEMBL1699424

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1699491	0.87	GAA (0.34)	MAPTKMT2AAKR1C3AKR1C2
	SCHEMBL1699600	0.82	MEN1 (0.40)	MAPTCCR2ALOX15CNR1MEN1
	SCHEMBL1699415	0.80	PTGDR2 (0.41)	PTGDR2MAPTRXFP1CCR2ALOX15
	SCHEMBL1699292	0.79	MAPT (0.34)	MAPTRXFP1MEN1KMT2ASMN1; SMN2
	SCHEMBL18860761	0.78	CCR2 (0.36)	PTGDR2RXFP1CCR2MEN1KMT2A
	SCHEMBL1699478	0.77	CCR2 (0.39)	CCR2ALOX15MEN1KMT2ASMN1; SMN2
	SCHEMBL1699394	0.77	TOP2A (0.34)	MAPTMEN1KMT2A
	SCHEMBL15099743	0.76	MAPT (0.31)	PTGDR2MAPTALOX15CNR1KMT2A
	SCHEMBL1699303	0.76	TBXAS1 (0.33)	MAPTMEN1KMT2A
	SCHEMBL1699312	0.76	ALOX15 (0.39)	CCR2ALOX15MEN1KMT2ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.