Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14049156 | 0.83 | DGAT1 (0.50) | DGAT1 | |
| SCHEMBL6369520 | 0.82 | DGAT1 (0.44) | DGAT1 | |
| SCHEMBL16940630 | 0.77 | DGAT1 (0.40) | DGAT1 | |
| SCHEMBL18589836 | 0.76 | DGAT1 (0.42) | DGAT1 | |
| SCHEMBL22962550 | 0.74 | DGAT1 (0.46) | DGAT1 | |
| SCHEMBL13904644 | 0.74 | DGAT1 (0.46) | DGAT1 | |
| SCHEMBL16684201 | 0.74 | DGAT1 (0.46) | DGAT1 | |
| SCHEMBL10098351 | 0.72 | DGAT1 (0.50) | DGAT1 | |
| SCHEMBL9120448 | 0.72 | DGAT1 (0.50) | DGAT1 | |
| SCHEMBL28133881 | 0.72 | DGAT1 (0.50) | DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180162956-A1 | WATER SOLUBLE NITRIC OXIDE-RELEASING POLYGLUCOSAMINES AND USES THEREOF | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | 2018-06-14 | — | — | US | disclosed |
| US-9850322-B2 | Water soluble nitric oxide-releasing polyglucosamines and uses thereof | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2017-12-26 | — | — | US | disclosed |
| US-9804168-B2 | Biomarker discovery in complex biological fluid using bead or particle based libraries and diagnostic kits and therapeutics | OPKO PHARMACEUTICALS, LLC (US) | 2017-10-31 | — | — | US | disclosed |
| US-20150225488-A1 | WATER SOLUBLE NITRIC OXIDE-RELEASING POLYGLUCOSAMINES AND USES THEREOF | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | 2015-08-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180162956-A1 | WATER SOLUBLE NITRIC OXIDE-RELEASING POLYGLUCOSAMINES AND USES THEREOF | NOS3, NOS2, NOS1 | DGAT1 3066/4885 |
| US-20150225488-A1 | WATER SOLUBLE NITRIC OXIDE-RELEASING POLYGLUCOSAMINES AND USES THEREOF | NOS3, NOS2, NOS1 | DGAT1 3066/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.