SCHEMBL1699591

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1699588	1.00	PIK3CA (0.44)	PIK3CASMN1; SMN2TSHRALDH1A1MAPT
	SCHEMBL15093309	0.81	KMT2A (0.47)	SMN1; SMN2ALDH1A1MAPTMEN1KMT2A
	SCHEMBL15093310	0.81	KMT2A (0.47)	SMN1; SMN2ALDH1A1MAPTMEN1KMT2A
	SCHEMBL28923911	0.78	PIK3CA (0.48)	PIK3CASMN1; SMN2TSHRALDH1A1MAPT
	SCHEMBL13221596	0.76	CA2 (0.51)	ALDH1A1MAPTNPSR1L3MBTL1MEN1
	SCHEMBL4764526	0.75	PIK3CA (0.47)	PIK3CATSHRALDH1A1MAPTKCNJ6
	SCHEMBL15093697	0.75	CTBP2 (0.46)	SMN1; SMN2ALDH1A1MAPTNPSR1L3MBTL1
	SCHEMBL15093699	0.75	CTBP2 (0.46)	SMN1; SMN2ALDH1A1MAPTNPSR1L3MBTL1
	SCHEMBL31353244	0.75	PRKCZ (0.39)	SMN1; SMN2ALDH1A1MAPTNPSR1MEN1
	SCHEMBL31353154	0.75	PRKCZ (0.39)	SMN1; SMN2ALDH1A1MAPTNPSR1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.