SCHEMBL16997288

SCHEMBL16997288

Cc1ccc(-c2nc(-c3ccc(C)c(-c4cccc5c4c4cc(-n6c7ccc(C)cc7c7cc(C)ccc76)ccc4n5-c4ccc(C)cc4)c3)nc(-c3ccc(C)c(-c4cccc5c4c4cc(-n6c7ccc(C)cc7c7cc(C)ccc76)ccc4n5-c4ccc(C)cc4)c3)n2)cc1

nearest known ligand 0.34

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TP53 P04637 2/20 0.34
TNKS2 Q9H2K2 1/20 0.31
HPGD P15428 1/20 0.31
PPARG P37231 1/20 0.31
NCOA2 Q15596 1/20 0.31
NCOA1 Q15788 1/20 0.31
AKR1C4 P17516 1/20 0.30
AKR1C3 P42330 1/20 0.30
AKR1C2 P52895 1/20 0.30
AKR1C1 Q04828 1/20 0.30
KDM4E B2RXH2 1/20 0.30
KMT2A Q03164 1/20 0.30
CSNK2A1 P68400 1/20 0.30
RXFP1 Q9HBX9 2/20 0.30
NPSR1 Q6W5P4 1/20 0.30
FLT3 P36888 1/20 0.30
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16997279 0.97 ALDH1A1 (0.34) TP53AKR1C4AKR1C3AKR1C2AKR1C1
SCHEMBL16997270 0.95 RXFP1 (0.35) TP53KMT2ARXFP1ALDH1A1
SCHEMBL16997286 0.92 ALDH1A1 (0.37) TP53AKR1C4AKR1C3AKR1C2AKR1C1
SCHEMBL16997278 0.92 AKR1C4 (0.36) TP53AKR1C4AKR1C3AKR1C2AKR1C1
SCHEMBL16997287 0.92 ALDH1A1 (0.37) TP53AKR1C4AKR1C3AKR1C2AKR1C1
SCHEMBL16997289 0.91 MAPT (0.37) TP53PPARGKMT2ARXFP1NPSR1
SCHEMBL16997266 0.88 L3MBTL1 (0.38) AKR1C4AKR1C3AKR1C2AKR1C1KDM4E
SCHEMBL16997277 0.87 RXFP1 (0.35) TP53AKR1C4AKR1C3AKR1C2AKR1C1
SCHEMBL16997275 0.85 RXRA (0.34) AKR1C4AKR1C3AKR1C2AKR1C1KMT2A
SCHEMBL16997282 0.84 KDM4E (0.36) AKR1C4AKR1C3AKR1C2AKR1C1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9911925-B2 Carbazole-based compound and organic light-emitting device including the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2018-03-06 US disclosed
US-9911925-B2 Carbazole-based compound and organic light-emitting device including the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2018-03-06 US disclosed
US-20150228908-A1 CARBAZOLE-BASED COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG SDI CO., LTD. (KR) 2015-08-13 US disclosed
US-20150228908-A1 CARBAZOLE-BASED COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG SDI CO., LTD. (KR) 2015-08-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150228908-A1 CARBAZOLE-BASED COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CYP1B1, CYP1A1, CRY1 TP53 2652/4885TNKS2 3491/4885HPGD 3665/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.