Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.30 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
| ▸ | BRD2 | P25440 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1282300 | 0.73 | DRD1 (0.39) | MEN1ALDH1A1GAAMAPTHPGD | |
| SCHEMBL6557292 | 0.72 | GPR84 (0.44) | GPR84ALDH1A1 | |
| SCHEMBL29463992 | 0.72 | GPR84 (0.44) | GPR84ALDH1A1 | |
| SCHEMBL24308956 | 0.72 | ALDH1A1 (0.47) | MEN1ALDH1A1GAAMAPTHPGD | |
| SCHEMBL18965964 | 0.71 | GPR84 (0.42) | GPR84ALDH1A1 | |
| SCHEMBL18965866 | 0.71 | GPR84 (0.42) | GPR84ALDH1A1 | |
| SCHEMBL1699767 | 0.67 | DRD2 (0.40) | MEN1ALDH1A1GAAMAPTHPGD | |
| SCHEMBL1709095 | 0.66 | HSD17B10 (0.35) | MEN1ALDH1A1GAAMAPTHPGD | |
| SCHEMBL11837962 | 0.65 | RAB9A (0.47) | MEN1ALDH1A1MAPTHPGDKMT2A | |
| SCHEMBL6643060 | 0.61 | NOTUM (0.44) | MEN1ALDH1A1GAAMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8691992-B2 | Octahydro biquinoline compound | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2014-04-08 | — | — | US | disclosed |
| US-8691992-B2 | Octahydro biquinoline compound | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2014-04-08 | — | — | US | disclosed |
| US-20120088916-A1 | OCTAHYDRO BIQUINOLINE COMPOUND | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2012-04-12 | — | — | US | disclosed |
| US-20120088916-A1 | OCTAHYDRO BIQUINOLINE COMPOUND | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2012-04-12 | — | — | US | disclosed |
| WO-2010132029-A1 | OCTAHYDRO BIQUINOLINE COMPOUND | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2010-11-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120088916-A1 | OCTAHYDRO BIQUINOLINE COMPOUND | CYP2S1, HCRTR2, CYP2B6 | GPR84 988/4885MEN1 3642/4885ALDH1A1 1988/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.