Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 12/20 | 0.49 |
| ▸ | RARA | P10276 | 12/20 | 0.49 |
| ▸ | RARG | P13631 | 11/20 | 0.49 |
| ▸ | RXRA | P19793 | 3/20 | 0.42 |
| ▸ | SMO | Q99835 | 2/20 | 0.38 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.37 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.36 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16998862 | 0.94 | RARB (0.55) | RARBRARARARGRXRASMO | |
| SCHEMBL20627746 | 0.89 | RARB (0.45) | RARBRARARARGRXRASMO | |
| SCHEMBL18961191 | 0.87 | RARA (0.47) | RARBRARARARGRXRAABCB1 | |
| SCHEMBL8514830 | 0.82 | RARA (0.40) | RARBRARARARGRXRA | |
| SCHEMBL4965729 | 0.80 | RARB (0.69) | RARBRARARARGRXRAABCB1 | |
| SCHEMBL8512658 | 0.80 | RARA (0.44) | RARBRARARARGRXRAABCB1 | |
| SCHEMBL15614873 | 0.78 | ASIC3 (0.40) | RARBRARARARGSMOASIC3 | |
| SCHEMBL8513486 | 0.78 | RARB (0.45) | RARBRARARARGRXRAABCB1 | |
| SCHEMBL16998412 | 0.77 | RARG (0.45) | RARBRARARARGRXRA | |
| SCHEMBL8513591 | 0.77 | RARA (0.38) | RARBRARARARGRXRAABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170170413-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2017-06-15 | — | — | US | disclosed |
| US-20170170413-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2017-06-15 | — | — | US | disclosed |
| WO-2015117718-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2015-08-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170170413-A1 | METAL COMPLEXES | SOD1, AP1M1, AP3M1 | RARB 3717/4885RARA 3284/4885RARG 3452/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.