SCHEMBL1700759

SCHEMBL1700759

COc1ccc(C(SC[C@H](N)C(=O)O)(c2ccccc2)c2ccccc2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 19/20 1.00
DNMT1 P26358 1/20 0.71

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14432747 1.00 KIF11 (1.00) KIF11DNMT1
SCHEMBL14432746 1.00 KIF11 (1.00) KIF11DNMT1
SCHEMBL14432855 0.91 KIF11 (0.83) KIF11DNMT1
SCHEMBL14432853 0.91 KIF11 (0.83) KIF11DNMT1
SCHEMBL15848679 0.90 KIF11 (0.80) KIF11DNMT1
SCHEMBL15848702 0.90 KIF11 (0.80) KIF11DNMT1
S-Trityl-L-Cysteine SCHEMBL768202 0.87 KIF11 (0.85) KIF11DNMT1
S-Trityl-L-Cysteine SCHEMBL768203 0.87 KIF11 (0.85) KIF11DNMT1
S-Trityl-L-Cysteine SCHEMBL6891349 0.87 KIF11 (0.85) KIF11DNMT1
SCHEMBL31438660 0.87 KIF11 (0.77) KIF11DNMT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025038669-A1 BICYCLIC MIMICS-RIGID, CELL PERMEABLE, SERUM STABLE HELICAL MIMICS THE TEXAS A&M UNIVERSITY SYSTEM (US) 2025-02-20 WO disclosed
US-12227542-B2 Method for producing peptide compound, protective group-forming reagent, and condensed polycyclic compound FUJIFILM CORPORATION (JP) 2025-02-18 US disclosed
CN-114524860-B ETELCALCETIDE synthesis method and application thereof 深圳翰宇药业股份有限公司 2025-01-24 CN disclosed
US-20240336655-A1 AMPHIPHILIC PEPTIDES FOR NUCLEIC ACID AND PROTEIN DELIVERY AJK BIOPHARMACEUTICAL LLC (US) 2024-10-10 US disclosed
US-20240033372-A1 MULTI-DRUG ANTIBODY DRUG CONJUGATES SEAGEN INC (US) 2024-02-01 US disclosed
US-20240002432-A1 METHOD FOR PRODUCING AMINO ACID OR PEPTIDE, PROTECTIVE GROUP-FORMING REAGENT, AND COMPOUND FUJIFILM CORPORATION (JP) 2024-01-04 US disclosed
WO-2023014909-A1 AMPHIPHILIC PEPTIDES FOR NUCLEIC ACID AND PROTEIN DELIVERY AJK Biopharmaceutical, LLC (US) 2023-02-09 WO disclosed
CN-110317188-B Compound and preparation method and application thereof 深圳翰宇药业股份有限公司 2023-01-17 CN disclosed
US-20230000999-A1 COMPOSITIONS AND METHODS FOR NUCLEIC ACID DELIVERY PARANG KEYKAVOUS (US) 2023-01-05 US disclosed
US-11541128-B2 Multi-drug antibody drug conjugates SEAGEN INC. (US) 2023-01-03 US disclosed
EP-2571496-A1 CONTROLLED DRUG RELEASE FROM DENDRIMERS Prolynx Llc (US) 2013-03-27 EP disclosed
EP-2566334-A1 CONTROLLED DRUG RELEASE FROM SOLID SUPPORTS Prolynx Llc (US) 2013-03-13 EP disclosed
US-8349899-B1 Selective inhibitors of EG5 motors and methods of use ARROWHEAD CENTER, INC. (US) 2013-01-08 US disclosed
US-8349899-B1 Selective inhibitors of EG5 motors and methods of use ARROWHEAD CENTER, INC. (US) 2013-01-08 US disclosed
US-8349899-B1 Selective inhibitors of EG5 motors and methods of use ARROWHEAD CENTER, INC. (US) 2013-01-08 US disclosed
WO-2011140376-A1 CONTROLLED DRUG RELEASE FROM DENDRIMERS PROLYNX LLC (US) 2011-11-10 WO disclosed
WO-2011140392-A1 CONTROLLED DRUG RELEASE FROM SOLID SUPPORTS PROLYNX LLC (US) 2011-11-10 WO disclosed
EP-1087992-B1 ANTITHROMBOTIC COMPOUNDS ORGANON NV (NL) 2008-08-20 EP disclosed
EP-1087992-A1 ANTITHROMBOTIC COMPOUNDS Akzo Nobel N.V. (NL) 2001-04-04 EP disclosed
WO-1999065934-A1 ANTITHROMBOTIC COMPOUNDS AKZO NOBEL N.V. (NL) 1999-12-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12227542-B2 Method for producing peptide compound, protective group-forming reagent, and condensed polycyclic compound C9, GRPR, VIP KIF11 3303/4885DNMT1 3331/4885
US-20240336655-A1 AMPHIPHILIC PEPTIDES FOR NUCLEIC ACID AND PROTEIN DELIVERY LNPEP, ZFR, SREBF1 KIF11 1634/4885DNMT1 1747/4885
US-20240002432-A1 METHOD FOR PRODUCING AMINO ACID OR PEPTIDE, PROTECTIVE GROUP-FORMING REAGENT, AND COMPOUND NGLY1, VIP, FPR1 KIF11 4721/4885DNMT1 4145/4885
US-20240033372-A1 MULTI-DRUG ANTIBODY DRUG CONJUGATES CDA, DCTD, MMAB KIF11 424/4885DNMT1 107/4885
US-20230000999-A1 COMPOSITIONS AND METHODS FOR NUCLEIC ACID DELIVERY ARGLU1, SLC7A11, PNISR KIF11 1611/4885DNMT1 1416/4885
US-11541128-B2 Multi-drug antibody drug conjugates CDA, DCTD, MMAB KIF11 443/4885DNMT1 91/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.