Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.56 |
| ▸ | ACHE | P22303 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| P-Xylene SCHEMBL27431590 | 1.00 | TDP1 (0.56) | TDP1TSHRNAPRTACHELMNA | |
| P-Xylene SCHEMBL93217 | 0.97 | TDP1 (0.53) | TDP1TSHRNAPRTACHELMNA | |
| P-Xylene SCHEMBL10614849 | 0.97 | TDP1 (0.53) | TDP1TSHRNAPRTACHELMNA | |
| P-Xylene SCHEMBL29229140 | 0.97 | TDP1 (0.53) | TDP1TSHRNAPRTACHELMNA | |
| P-Xylene SCHEMBL20640077 | 0.94 | TDP1 (0.50) | TDP1TSHRNAPRTACHELMNA | |
| Toluene SCHEMBL434901 | 0.91 | ACHE (0.65) | TDP1TSHRNAPRTACHELMNA | |
| Pyridine SCHEMBL5590769 | 0.91 | TSHR (0.53) | TDP1TSHRNAPRTACHELMNA | |
| SCHEMBL19443810 | 0.88 | TSHR (0.61) | TDP1TSHRNAPRTACHELMNA | |
| Toluene SCHEMBL27614086 | 0.88 | ACHE (0.61) | TDP1TSHRNAPRTACHELMNA | |
| Toluene SCHEMBL27623492 | 0.88 | ACHE (0.61) | TDP1TSHRNAPRTACHELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2582741-B1 | BORONATED POLYMERS | UNIV TWENTE (NL) | 2016-07-27 | — | — | EP | disclosed |
| CN-104109712-A | Methods and materials using signaling probes | CHROMOCELL CORP | 2014-10-22 | — | — | CN | disclosed |
| US-20130157926-A1 | BORONATED POLYMERS | UNIVERSITEIT TWENTE (NL) | 2013-06-20 | — | — | US | disclosed |
| EP-2582741-A2 | BORONATED POLYMERS | Universiteit Twente (NL) | 2013-04-24 | — | — | EP | disclosed |
| WO-2011159161-A2 | BORONATED POLYMERS | UNIVERSITEIT TWENTE (NL) | 2011-12-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130157926-A1 | BORONATED POLYMERS | PHB1, ABCB11, PHB2 | TDP1 215/4885TSHR 2215/4885NAPRT 2212/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.