Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 1/20 | 0.42 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.42 |
| ▸ | ALKBH1 | Q13686 | 3/20 | 0.42 |
| ▸ | MERTK | Q12866 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.38 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5883689 | 0.86 | ALKBH1 (0.51) | PRMT5WDR77ALKBH1PKMCYP1A2 | |
| SCHEMBL4701633 | 0.86 | HPGD (0.50) | L3MBTL1ALDH1A1TSHR | |
| SCHEMBL17226623 | 0.75 | HSD11B1 (0.45) | PRMT5WDR77PKMPDE1CCYP1A2 | |
| SCHEMBL148140 | 0.75 | NPC1 (0.48) | ALKBH1CYP1A2HTTALDH1A1LRRK2 | |
| SCHEMBL10961245 | 0.74 | ALKBH1 (0.41) | PRMT5WDR77ALKBH1PKML3MBTL1 | |
| SCHEMBL1758500 | 0.73 | MAPK14 (0.44) | ALKBH1PKML3MBTL1P4HTMALDH1A1 | |
| SCHEMBL23087256 | 0.73 | PRMT5 (0.45) | PRMT5WDR77PKML3MBTL1CYP1A2 | |
| SCHEMBL31002249 | 0.73 | PKM (0.44) | PRMT5WDR77PKML3MBTL1CYP1A2 | |
| SCHEMBL14318903 | 0.72 | CYP1A2 (0.45) | PRMT5WDR77PKML3MBTL1CYP1A2 | |
| SCHEMBL14973158 | 0.72 | MAOB (0.46) | MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1516874-B1 | Fungicidal heterocyclic aromatic amides and their compositions, methods of use and preparation | DOW AGROSCIENCES LLC (US) | 2015-08-19 | — | — | EP | disclosed |