SCHEMBL148140

SCHEMBL148140

Cn1ncc(C(=O)c2ccc(Cl)cc2Cl)c1OCc1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.48
RAB9A P51151 1/20 0.48
CYP2C9 P11712 2/20 0.46
CYP1A2 P05177 1/20 0.46
CYP2D6 P10635 1/20 0.46
CYP2C19 P33261 1/20 0.46
ALDH1A1 P00352 2/20 0.43
HTR2A P28223 1/20 0.43
HTR2C P28335 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
HSD17B10 Q99714 1/20 0.43
KDM4E B2RXH2 2/20 0.42
TDP1 Q9NUW8 2/20 0.42
ALKBH1 Q13686 1/20 0.42
CNR1 P21554 4/20 0.41
PAK1 Q13153 1/20 0.41
PTGER1 P34995 2/20 0.41
MEN1 O00255 1/20 0.40
POLB P06746 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10958795 0.93 PAK1 (0.44) RAB9ACYP2C9CYP1A2CYP2D6CYP2C19
SCHEMBL10960396 0.90 PAK1 (0.42) NPC1RAB9ACYP2C9CYP1A2CYP2D6
SCHEMBL10958739 0.88 MAOA (0.47) RAB9ACYP2C9CYP1A2CYP2C19ALDH1A1
SCHEMBL10958570 0.88 PRMT5 (0.43) CYP2C9CYP1A2CYP2D6CYP2C19ALDH1A1
SCHEMBL10673937 0.87 NPC1 (0.46) NPC1RAB9ACYP2C9CYP1A2CYP2D6
SCHEMBL10668454 0.87 RAB9A (0.46) NPC1RAB9ACYP2C9CYP1A2CYP2D6
SCHEMBL10961015 0.86 P2RX7 (0.42) CYP2C9CYP1A2CYP2D6CYP2C19ALDH1A1
SCHEMBL11118281 0.86 HPGD (0.49) NPC1RAB9AALDH1A1NPSR1SMN1; SMN2
SCHEMBL10958612 0.86 NPSR1 (0.45) ALDH1A1NPSR1SMN1; SMN2KDM4ETDP1
SCHEMBL10960980 0.85 TDP1 (0.44) CYP2C9CYP1A2CYP2D6CYP2C19ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1905 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3599857-B1 HERBICIDAL MIXTURES BAYER AG (DE) 2023-08-23 EP claimed
CN-110461157-B Herbicidal mixtures 拜耳公司 2021-11-02 CN claimed
US-20210289781-A1 HERBICIDAL MIXTURES BAYER AKTIENGESELLSCHAFT (DE) 2021-09-23 US claimed
US-20210137117-A1 HERBICIDAL MIXTURES FMC CORPORATION 2021-05-13 US claimed
CN-112469277-A Herbicidal mixtures comprising aclonifen and cinmethylin 拜耳公司 2021-03-09 CN claimed
US-10932467-B2 Herbicidal mixtures BAYER AKTIENGESELLSCHAFT (DE) 2021-03-02 US claimed
US-20140310835-A1 SOYBEAN EVENT SYHT04R AND COMPOSITIONS AND METHODS FOR DETECTION THEREOF SYNGENTA PARTICIPATIONS AG (CH) 2014-10-16 US claimed
US-20140208463-A1 ACTIVE COMPOUND COMBINATIONS COMPRISING SPECIFIC TETRAMIC ACID DERIVATIVES BAYER INTELLECTUAL PROPERTY GMBH (DE) 2014-07-24 US claimed
WO-2012082542-A2 SOYBEAN EVENT SYHT04R AND COMPOSITIONS AND METHODS FOR DETECTION THEREOF SYNGENTA PARTICIPATIONS AG (CH) 2012-06-21 WO claimed
JP-1193202-A None JP disclosed
JP-58185568-A None JP disclosed
JP-62169706-A None JP disclosed
JP-1113304-A None JP disclosed
US-20260144250-A1 SOLVENT-FREE FORMULATIONS OF LOW-MELTING ACTIVE INGREDIENTS BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2026-05-28 US disclosed
EP-0414511-A1 Thiadiazole derivatives and herbicide compositions containing the same Tosoh Corporation (JP) 1991-02-27 EP disclosed
JP-H01193202-A HERBICIDE COMPOSITION FOR PADDY FIELD TOSOH CORP 1989-08-03 JP disclosed
JP-H01113304-A HERBICIDAL COMPOSITION DAIKIN IND LTD 1989-05-02 JP disclosed
JP-S62169706-A HERBICIDAL COMPOSITION NISSAN CHEM IND LTD 1987-07-25 JP disclosed
US-4557753-A Herbicidal 4-benzoyl-1-methyl-5-phenylalkoxy pyrazoles NISSAN CHEMICAL INDUSTRIES LTD. (JP) 1985-12-10 US disclosed
JP-S58185568-A PYRAZOLE DERIVATIVE, ITS PREPARATION AND SELECTIVE HERBICIDE CONTAINING SAID DERIVATIVE NISSAN CHEM IND LTD 1983-10-29 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260144250-A1 SOLVENT-FREE FORMULATIONS OF LOW-MELTING ACTIVE INGREDIENTS FOXM1, CSDE1, RCC1 NPC1 2719/4885RAB9A 3200/4885CYP2C9 269/4885
US-20210289781-A1 HERBICIDAL MIXTURES ATL3, DDT, CLSPN NPC1 4471/4885RAB9A 4434/4885CYP2C9 973/4885
US-10932467-B2 Herbicidal mixtures DDT, PRDX5, DHX35 NPC1 4880/4885RAB9A 4108/4885CYP2C9 99/4885
US-20210137117-A1 HERBICIDAL MIXTURES DDT, MTX2, ATL3 NPC1 4750/4885RAB9A 4287/4885CYP2C9 390/4885
US-20140208463-A1 ACTIVE COMPOUND COMBINATIONS COMPRISING SPECIFIC TETRAMIC ACID DERIVATIVES DDT, TBCA, CA3 NPC1 4028/4885RAB9A 2282/4885CYP2C9 73/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.