Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNB2 | O95067 | 8/20 | 0.37 |
| ▸ | CDK1 | P06493 | 8/20 | 0.37 |
| ▸ | CCNB1 | P14635 | 8/20 | 0.37 |
| ▸ | CCNB3 | Q8WWL7 | 8/20 | 0.37 |
| ▸ | CDK5 | Q00535 | 4/20 | 0.37 |
| ▸ | CDK5R1 | Q15078 | 4/20 | 0.37 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14867641 | 0.89 | CCNB2 (0.32) | CCNB2CDK1CCNB1CCNB3CDK5 | |
| SCHEMBL20051998 | 0.85 | CCNB2 (0.35) | CCNB2CDK1CCNB1CCNB3CDK5 | |
| SCHEMBL17014883 | 0.76 | KDM4E (0.39) | CCNB2CDK1CCNB1CCNB3CDK5 | |
| SCHEMBL13896532 | 0.73 | AHCY (0.40) | CCNB2CDK1CCNB1CCNB3CDK2 | |
| SCHEMBL13443480 | 0.72 | L3MBTL1 (0.36) | CCNB2CDK1CCNB1CCNB3CDK5 | |
| SCHEMBL14867658 | 0.72 | KDM4E (0.35) | KDM4EMEN1KMT2AL3MBTL1 | |
| SCHEMBL23547997 | 0.72 | CCNB2 (0.35) | CCNB2CDK1CCNB1CCNB3CDK5 | |
| SCHEMBL25605580 | 0.72 | CCNB2 (0.35) | CCNB2CDK1CCNB1CCNB3CDK5 | |
| SCHEMBL22759882 | 0.72 | CCNB2 (0.35) | CCNB2CDK1CCNB1CCNB3CDK5 | |
| SCHEMBL12416177 | 0.71 | PRMT6 (0.36) | ADORA3ADORA2AADORA1PRMT6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9303260-B2 | UNA duplex oligomers for therapeutics | ARCTURUS THERAPEUTICS, INC. (US) | 2016-04-05 | — | — | US | disclosed |
| US-20150232849-A1 | UNA DUPLEX OLIGOMERS FOR THERAPEUTICS | MARINA BIOTECH, INC. | 2015-08-20 | — | — | US | disclosed |