Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.74 |
| ▸ | MEN1 | O00255 | 1/20 | 0.74 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | PIR | O00625 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.40 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.40 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.40 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17996453 | 0.85 | KMT2A (1.00) | KMT2AMEN1CYP2C19ALDH1A1TDP1 | |
| SCHEMBL17015171 | 0.85 | KMT2A (1.00) | KMT2AMEN1CYP2C19ALDH1A1TDP1 | |
| SCHEMBL16317067 | 0.83 | CYP2C19 (1.00) | KMT2AMEN1CYP2C19ALDH1A1TDP1 | |
| SCHEMBL17015173 | 0.83 | CYP2C19 (1.00) | KMT2AMEN1CYP2C19ALDH1A1TDP1 | |
| SCHEMBL10904698 | 0.77 | CYP2C19 (0.69) | KMT2AMEN1CYP2C19ALDH1A1TDP1 | |
| SCHEMBL2940445 | 0.76 | CYP2C19 (0.84) | KMT2AMEN1CYP2C19ALDH1A1TDP1 | |
| SCHEMBL1774946 | 0.76 | CYP2C19 (0.84) | KMT2AMEN1CYP2C19ALDH1A1TDP1 | |
| SCHEMBL1774945 | 0.76 | CYP2C19 (0.84) | KMT2AMEN1CYP2C19ALDH1A1TDP1 | |
| SCHEMBL17020444 | 0.74 | CYP2C19 (0.79) | KMT2AMEN1CYP2C19ALDH1A1TDP1 | |
| SCHEMBL16317068 | 0.74 | CYP2C19 (0.79) | KMT2AMEN1CYP2C19ALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160355852-A1 | METHODS AND SYSTEMS FOR SULFIMIDATION OR SULFOXIMIDATION OF ORGANIC MOLECULES | THE CALIFORNIA INSTITUTE OF TECHNOLOGY | 2016-12-08 | — | — | US | disclosed |
| US-20160355852-A1 | METHODS AND SYSTEMS FOR SULFIMIDATION OR SULFOXIMIDATION OF ORGANIC MOLECULES | THE CALIFORNIA INSTITUTE OF TECHNOLOGY | 2016-12-08 | — | — | US | disclosed |
| US-9399762-B2 | Methods and systems for sulfimidation or sulfoximidation of organic molecules | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2016-07-26 | — | — | US | disclosed |
| US-9399762-B2 | Methods and systems for sulfimidation or sulfoximidation of organic molecules | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2016-07-26 | — | — | US | disclosed |
| US-20150232814-A1 | METHODS AND SYSTEMS FOR SULFIMIDATION OR SULFOXIMIDATION OF ORGANIC MOLECULES | NAVY, SECRETARY OF THE UNITED STATES OF AMERICA | 2015-08-20 | — | — | US | disclosed |
| US-20150232814-A1 | METHODS AND SYSTEMS FOR SULFIMIDATION OR SULFOXIMIDATION OF ORGANIC MOLECULES | NAVY, SECRETARY OF THE UNITED STATES OF AMERICA | 2015-08-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150232814-A1 | METHODS AND SYSTEMS FOR SULFIMIDATION OR SULFOXIMIDATION OF ORGANIC MOLECULES | TST, STS, MPST | KMT2A 3084/4885MEN1 3530/4885CYP2C19 2262/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.