Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | METAP1 | P53582 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | ALKBH3 | Q96Q83 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16253974 | 0.92 | METAP1 (0.47) | MEN1KMT2AALDH1A1KDM4EMAOB | |
| SCHEMBL17016644 | 0.80 | KDM4E (0.36) | ALDH1A1KDM4EMAOBCA1CA2 | |
| SCHEMBL388758 | 0.78 | PGR (0.53) | MEN1KMT2AALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL19054676 | 0.75 | ALDH1A1 (0.43) | MEN1KMT2AALDH1A1KDM4EMAOB | |
| SCHEMBL12723065 | 0.74 | ACHE (0.45) | MEN1KMT2AALDH1A1KDM4EMAOB | |
| SCHEMBL11822087 | 0.72 | PDE3B (0.43) | ALDH1A1KDM4EMAOBSMN1; SMN2METAP1 | |
| SCHEMBL2997926 | 0.72 | ALKBH3 (0.58) | ALDH1A1MAOBMETAP1CA1CA2 | |
| SCHEMBL3368868 | 0.72 | PGR (0.69) | MEN1KMT2AALDH1A1KDM4EMAOB | |
| SCHEMBL15483667 | 0.71 | METAP1 (0.63) | MEN1KMT2AALDH1A1KDM4EMAOB | |
| SCHEMBL29981141 | 0.70 | DYRK1A (0.47) | MEN1KMT2AALDH1A1KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9919304-B2 | Sulfonyl-containing polymers based on free-radically polymerizable spirobisindane monomers | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2018-03-20 | — | — | US | disclosed |
| US-9919305-B2 | Sulfonyl-containing polymeric material with rigid and contorted divinyl crosslinker | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2018-03-20 | — | — | US | disclosed |
| US-20170333870-A1 | POLYMERIC MATERIALS FOR CAPTURING FORMALDEHYDE | 3M INNOVATIVE PROPERTIES COMPANY | 2017-11-23 | — | — | US | disclosed |
| US-20170182475-A1 | SULFONIC ACID-CONTAINING POLYMERIC MATERIALS AS AMINE SORBENTS | 3M INNOVATIVE PROPERTIES COMPANY | 2017-06-29 | — | — | US | disclosed |
| US-9463454-B2 | Amino-containing polymeric material with rigid and contorted divinyl crosslinker | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2016-10-11 | — | — | US | disclosed |
| US-20160121321-A1 | AMINO-CONTAINING POLYMERIC MATERIAL WITH RIGID AND CONTORTED DIVINYL CROSSLINKER | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2016-05-05 | — | — | US | disclosed |
| US-20160089667-A1 | SULFONYL-CONTAINING POLYMERS BASED ON FREE-RADICALLY POLYMERIZABLE SPIROBISINDANE MONOMERS | 3M INNOVATIVE PROPERTIES COMPANY | 2016-03-31 | — | — | US | disclosed |
| US-9296668-B2 | Polymerizable spirobisindane monomers and polymers prepared therefrom | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2016-03-29 | — | — | US | disclosed |
| US-20160082429-A1 | SULFONYL-CONTAINING POLYMERIC MATERIAL WITH RIGID AND CONTORTED DIVINYL CROSSLINKER | 3M INNOVATIVE PROPERTIES COMPANY | 2016-03-24 | — | — | US | disclosed |
| US-9139674-B2 | Rigid and contorted divinyl crosslinkers | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2015-09-22 | — | — | US | disclosed |
| US-20150239806-A1 | POLYMERIZABLE SPIROBISINDANE MONOMERS AND POLYMERS PREPARED THEREFROM | 3M INNOVATIVE PROPERTIES COMPANY | 2015-08-27 | — | — | US | disclosed |
| US-20150232592-A1 | RIGID AND CONTORTED DIVINYL CROSSLINKERS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2015-08-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150239806-A1 | POLYMERIZABLE SPIROBISINDANE MONOMERS AND POLYMERS PREPARED THEREFROM | WEE1, PKD1, WEE2 | MEN1 2350/4885KMT2A 3729/4885ALDH1A1 792/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.