Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | RAD52 | P43351 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 5/20 | 0.35 |
| ▸ | DRD3 | P35462 | 5/20 | 0.35 |
| ▸ | HTR1D | P28221 | 2/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | GPR3 | P46089 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 5/20 | 0.34 |
| ▸ | DRD4 | P21917 | 4/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | HTR7 | P34969 | 1/20 | 0.34 |
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17020540 | 0.92 | HSD11B1 (0.37) | KDM4EHSD11B1DRD2DRD3HTR1D | |
| SCHEMBL1091438 | 0.82 | PGR (0.45) | KDM4EHSD11B1DRD2DRD3HTR1D | |
| SCHEMBL17016643 | 0.80 | MEN1 (0.42) | KDM4EPGRALDH1A1MAOBCA1 | |
| SCHEMBL17016648 | 0.77 | NPSR1 (0.37) | HSD11B1DRD2DRD3HTR1DGPR3 | |
| SCHEMBL15280722 | 0.76 | HTR1D (0.36) | HSD11B1DRD2DRD3HTR1DCHRM1 | |
| SCHEMBL17016647 | 0.75 | HSD11B1 (0.36) | HSD11B1DRD2DRD3HTR1DGPR3 | |
| SCHEMBL1807301 | 0.74 | DRD2 (0.39) | HSD11B1DRD2DRD3HTR1DCHRM1 | |
| SCHEMBL8771675 | 0.74 | DRD2 (0.39) | KDM4EHSD11B1DRD2DRD3HTR1D | |
| SCHEMBL31476394 | 0.73 | CXCR2 (0.42) | HSD11B1DRD2DRD3HTR1DCHRM1 | |
| SCHEMBL18030872 | 0.72 | CHRM1 (0.31) | DRD2DRD3CHRM1DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9296668-B2 | Polymerizable spirobisindane monomers and polymers prepared therefrom | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2016-03-29 | — | — | US | disclosed |
| US-9139674-B2 | Rigid and contorted divinyl crosslinkers | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2015-09-22 | — | — | US | disclosed |
| US-20150239806-A1 | POLYMERIZABLE SPIROBISINDANE MONOMERS AND POLYMERS PREPARED THEREFROM | 3M INNOVATIVE PROPERTIES COMPANY | 2015-08-27 | — | — | US | disclosed |
| US-20150232592-A1 | RIGID AND CONTORTED DIVINYL CROSSLINKERS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2015-08-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150239806-A1 | POLYMERIZABLE SPIROBISINDANE MONOMERS AND POLYMERS PREPARED THEREFROM | WEE1, PKD1, WEE2 | KDM4E 4454/4885RAD52 1346/4885ATM 3530/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.