Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 6/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 5/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | EGLN2 | Q96KS0 | 6/20 | 0.39 |
| ▸ | OXTR | P30559 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.34 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 2/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2154193 | 0.78 | CYP11B2 (0.53) | CYP11B2CYP11B1EGLN2ALDH1A1CYP2A6 | |
| SCHEMBL17021842 | 0.77 | APP (0.40) | CYP11B2CYP11B1APPEGLN2ALDH1A1 | |
| SCHEMBL3511128 | 0.71 | TTR (0.41) | APPALDH1A1CYP2A6 | |
| SCHEMBL7634772 | 0.71 | ALDH1A1 (0.48) | CYP11B2CYP11B1EGLN2ALDH1A1CYP2A6 | |
| SCHEMBL1550258 | 0.71 | ALDH1A1 (0.43) | CYP11B2CYP11B1APPEGLN2ALDH1A1 | |
| SCHEMBL14926516 | 0.69 | CYP11B2 (0.47) | CYP11B2CYP11B1EGLN2ALDH1A1CYP2A6 | |
| SCHEMBL27806613 | 0.69 | KIF11 (0.47) | CYP11B2CYP11B1EGLN2ALDH1A1CYP2A6 | |
| SCHEMBL5370107 | 0.69 | CYP11B2 (0.41) | CYP11B2CYP11B1EGLN2ALDH1A1CYP2A6 | |
| SCHEMBL13990206 | 0.69 | TSHR (0.48) | APPALDH1A1 | |
| SCHEMBL23625527 | 0.68 | ALDH1A1 (0.56) | CYP11B2CYP11B1EGLN2ALDH1A1CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015121241-A1 | ORGANIC TADF MOLECULES HAVING STERIC HINDRANCE AT THE DONOR AND AT THE ACCEPTOR FOR OPTOELECTRONIC DEVICES | YERSIN, HARTMUT (DE) | 2015-08-20 | — | — | WO | disclosed |