Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 8/20 | 0.47 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 2/20 | 0.43 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | ITGB1 | P05556 | 3/20 | 0.42 |
| ▸ | ITGA4 | P13612 | 3/20 | 0.42 |
| ▸ | MMP3 | P08254 | 2/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3156701 | 0.83 | ALDH1A1 (0.54) | PPARGKEAP1PPARAALDH1A1ALOX15 | |
| SCHEMBL428265 | 0.83 | ALDH1A1 (0.54) | PPARGKEAP1PPARAALDH1A1ALOX15 | |
| SCHEMBL1702385 | 0.79 | FPR2 (0.55) | PPARGPPARAALDH1A1ALOX15MMP3 | |
| SCHEMBL14601306 | 0.73 | LDHA (0.49) | PPARGPPARAMMP3 | |
| SCHEMBL12568266 | 0.73 | PTPN1 (0.55) | PPARGPPARAALDH1A1ALOX15ITGB1 | |
| SCHEMBL15219934 | 0.73 | KDM4E (0.42) | PPARGPPARAITGB1ITGA4MMP3 | |
| SCHEMBL8222429 | 0.73 | KDM4E (0.42) | PPARGPPARAITGB1ITGA4MMP3 | |
| SCHEMBL30040624 | 0.72 | TPH1 (0.54) | PPARGPPARA | |
| SCHEMBL429637 | 0.72 | TPH1 (0.54) | PPARGPPARA | |
| SCHEMBL2000467 | 0.72 | TPH1 (0.54) | PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2231701-B1 | PEPTIDOMIMETICS WITH GLUCAGON ANTAGONISTIC AND GLP-1 AGONISTIC ACTIVITIES | CADILA HEALTHCARE LTD (IN) | 2012-04-18 | — | — | EP | disclosed |