Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | VCAM1 | P19320 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.38 |
| ▸ | XDH | P47989 | 1/20 | 0.37 |
| ▸ | AR | P10275 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17060395 | 0.80 | CNR2 (0.37) | LMNAALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL15732879 | 0.76 | NQO2 (0.37) | LMNAGAAALDH1A1MAPTMEN1 | |
| SCHEMBL2479169 | 0.74 | HTR7 (0.47) | MAPT | |
| SCHEMBL2476855 | 0.73 | GRM2 (0.38) | LMNAMEN1KMT2AGRM2AR | |
| SCHEMBL17023236 | 0.71 | HTR7 (0.59) | MAPTAR | |
| SCHEMBL27912918 | 0.71 | GLO1 (0.47) | LMNAALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL17060308 | 0.70 | CNR2 (0.34) | LMNAALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL17060309 | 0.70 | CNR2 (0.34) | LMNAALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL17060287 | 0.70 | NQO2 (0.38) | LMNAALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL15732940 | 0.69 | DGAT1 (0.43) | LMNAGAAALDH1A1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2007756-B1 | MODULATORS OF ATP-BINDING CASSETTE TRANSPORTERS | VERTEX PHARMA (US) | 2015-08-26 | — | — | EP | disclosed |