Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4455107 | 0.88 | — | — | |
| SCHEMBL4014164 | 0.68 | SHMT2 (0.40) | — | |
| SCHEMBL2231818 | 0.68 | — | — | |
| SCHEMBL5475421 | 0.68 | SHMT2 (0.40) | — | |
| SCHEMBL30708579 | 0.68 | — | — | |
| SCHEMBL556889 | 0.66 | SIGMAR1 (0.43) | SIGMAR1 | |
| SCHEMBL29460883 | 0.66 | SIGMAR1 (0.43) | SIGMAR1 | |
| SCHEMBL29438246 | 0.66 | — | — | |
| SCHEMBL35277 | 0.66 | — | — | |
| SCHEMBL12833371 | 0.64 | SIGMAR1 (0.52) | SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6596727-B1 | Substituted 4-amino- and 4-alkoxy-cycloalkylpyrimidines, processes for their preparation, and their use as pesticides and fungicides control of pests and as fungicides. | HOECHST AKTIENGESELLSCHAFT (DE) | 2003-07-22 | — | — | US | claimed |
| JP-2619606-B2 | — | HOECHST AG (DE) | 1997-06-11 | — | — | JP | claimed |
| EP-0631575-A1 | SUBSTITUTED PYRIMIDINES AND THEIR USE AS PESTICIDES | Hoechst Schering AgrEvo GmbH (DE) | 1995-01-04 | — | — | EP | claimed |
| WO-1993019050-A1 | SUBSTITUTED PYRIMIDINES AND THEIR USE AS PESTICIDES | HOECHST SCHERING AGREVO GMBH (DE) | 1993-09-30 | — | — | WO | claimed |
| EP-1663994-B1 | TETRAHYDROQUINAZOLINE COMPOUNDS AS INHIBITORS OF VOLTAGE-GATED ION CHANNELS | VERTEX PHARMA (US) | 2012-03-07 | — | — | EP | disclosed |
| US-6596727-B1 | Substituted 4-amino- and 4-alkoxy-cycloalkylpyrimidines, processes for their preparation, and their use as pesticides and fungicides control of pests and as fungicides. | HOECHST AKTIENGESELLSCHAFT (DE) | 2003-07-22 | — | — | US | disclosed |
| US-5571815-A | Substituted pyrimidines, process for their preparation, and their use as pesticides and fungicides | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-11-05 | — | — | US | disclosed |
| EP-0631575-A1 | SUBSTITUTED PYRIMIDINES AND THEIR USE AS PESTICIDES | Hoechst Schering AgrEvo GmbH (DE) | 1995-01-04 | — | — | EP | disclosed |
| WO-1993019050-A1 | SUBSTITUTED PYRIMIDINES AND THEIR USE AS PESTICIDES | HOECHST SCHERING AGREVO GMBH (DE) | 1993-09-30 | — | — | WO | disclosed |