SCHEMBL17028629

SCHEMBL17028629

CCC(CC(=O)O)c1ccc(OCc2cc(F)ccc2Br)cc1

nearest known ligand 0.56

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 15/20 0.56
FNTA P49354 1/20 0.43
FNTB P49356 1/20 0.43
MAOB P27338 1/20 0.42
FFAR4 Q5NUL3 5/20 0.41
ALDH1A1 P00352 1/20 0.40
GAA P10253 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17028721 0.80 FFAR4 (0.46) FFAR1MAOBFFAR4ALDH1A1
SCHEMBL17028705 0.79 FFAR1 (0.51) FFAR1FFAR4
SCHEMBL17028627 0.77 PPARA (0.52) FFAR1FFAR4
SCHEMBL5378079 0.75 FFAR1 (0.52) FFAR1FNTAFNTBALDH1A1
SCHEMBL17028719 0.73 FFAR4 (0.49) FFAR1MAOBFFAR4
SCHEMBL13118253 0.72 FFAR1 (1.00) FFAR1
SCHEMBL28628025 0.71 FFAR1 (0.59) FFAR1ALDH1A1GAA
SCHEMBL15265930 0.70 FFAR4 (0.53) FFAR1MAOBFFAR4
SCHEMBL4453571 0.70 FFAR1 (0.78) FFAR1FNTAFNTBGAA
SCHEMBL15265470 0.70 FFAR4 (0.53) FFAR1FFAR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3107901-B1 COMPOUNDS FOR USE AS GPR120 AGONISTS PIRAMAL ENTPR LTD (IN) 2020-04-01 EP disclosed
US-10227360-B2 Compounds for use as GPR120 agonists Piramal Enterprises Limited (IN) 2019-03-12 US disclosed
EP-3107901-A1 COMPOUNDS FOR USE AS GPR120 AGONISTS Piramal Enterprises Limited (IN) 2016-12-28 EP disclosed
US-20160347768-A1 COMPOUNDS FOR USE AS GPR120 AGONISTS Piramal Enterprises Limited (IN) 2016-12-01 US disclosed
WO-2015125085-A1 COMPOUNDS FOR USE AS GPR120 AGONISTS Piramal Enterprises Limited (IN) 2015-08-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10227360-B2 Compounds for use as GPR120 agonists GPR119, GPR55, GPR180 FFAR1 11/4885FNTA 1393/4885FNTB 1779/4885
US-20160347768-A1 COMPOUNDS FOR USE AS GPR120 AGONISTS GPR119, GPR55, GPR180 FFAR1 11/4885FNTA 1393/4885FNTB 1779/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.