Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 2/20 | 0.45 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.45 |
| ▸ | NMT1 | P30419 | 5/20 | 0.42 |
| ▸ | NMT2 | O60551 | 4/20 | 0.42 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | PLG | P00747 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.40 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | TLR2 | O60603 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25559845 | 0.88 | PTGS1 (0.47) | ITGB3ITGA2BNMT1NMT2SLC6A5 | |
| SCHEMBL17177670 | 0.85 | ITGB3 (0.43) | ITGB3ITGA2BEPHX2PTGS1GSTK1 | |
| SCHEMBL17029467 | 0.81 | ITGB3 (0.53) | ITGB3ITGA2BPTPN1GRIA1 | |
| SCHEMBL21320323 | 0.81 | PTGS1 (0.49) | ITGB3ITGA2BALDH1A1LMNARECQL | |
| SCHEMBL18515902 | 0.81 | PTGS1 (0.49) | ITGB3ITGA2BALDH1A1LMNARECQL | |
| SCHEMBL3052861 | 0.81 | LPAR3 (0.45) | SLC6A5MEN1KMT2AEPHX2TLR2 | |
| SCHEMBL21320215 | 0.79 | EPHX2 (0.53) | ITGB3ITGA2BSLC6A5MEN1KMT2A | |
| SCHEMBL17177503 | 0.79 | MEN1 (0.47) | ITGB3ITGA2BNMT1NMT2SLC6A5 | |
| SCHEMBL17177497 | 0.79 | MAOA (0.50) | SLC6A5MEN1ALDH1A1PLGLMNA | |
| SCHEMBL4637261 | 0.79 | FAAH (0.51) | SLC6A5MEN1KMT2AEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2910573-A1 | ANTIBODY-DRUG CONJUGATE PRODUCED BY BINDING THROUGH LINKER HAVING HYDROPHILIC STRUCTURE | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2015-08-26 | — | — | EP | disclosed |