Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 2/20 | 0.53 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.53 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.51 |
| ▸ | CHRND | Q07001 | 4/20 | 0.48 |
| ▸ | CHRNA1 | P02708 | 3/20 | 0.48 |
| ▸ | CHRNG | P07510 | 3/20 | 0.48 |
| ▸ | CHRNB1 | P11230 | 3/20 | 0.48 |
| ▸ | MMP2 | P08253 | 1/20 | 0.48 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.48 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.48 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.48 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.48 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25874361 | 0.84 | MMP2 (0.56) | CHRNDCHRNA1CHRNGCHRNB1MMP2 | |
| SCHEMBL38659045 | 0.84 | CHRND (0.59) | CHRNDCHRNA1CHRNGCHRNB1MMP2 | |
| SCHEMBL29313314 | 0.83 | QRFPR (0.49) | — | |
| SCHEMBL29313281 | 0.83 | QRFPR (0.49) | — | |
| SCHEMBL16485208 | 0.82 | MMP2 (0.60) | ITGB3ITGA2BCHRNDCHRNA1CHRNG | |
| SCHEMBL27273355 | 0.82 | QRFPR (0.48) | — | |
| SCHEMBL17029441 | 0.81 | ITGB3 (0.45) | ITGB3ITGA2BPTPN1GRIA1 | |
| SCHEMBL17128773 | 0.81 | CHRNB2 (0.56) | ITGB3ITGA2BCHRNDCHRNA1CHRNG | |
| SCHEMBL16485202 | 0.81 | CHRNB2 (0.56) | ITGB3ITGA2BCHRNDCHRNA1CHRNG | |
| SCHEMBL17029474 | 0.81 | CHRNB2 (0.54) | ITGB3ITGA2BCHRNDCHRNA1CHRNG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2910573-A1 | ANTIBODY-DRUG CONJUGATE PRODUCED BY BINDING THROUGH LINKER HAVING HYDROPHILIC STRUCTURE | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2015-08-26 | — | — | EP | disclosed |