Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | APP | P05067 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | TGM2 | P21980 | 1/20 | 0.32 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.32 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.32 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1421154 | 1.00 | AKT1 (0.45) | AKT1ALDH1A1APPLMNAMAPT | |
| SCHEMBL8152965 | 0.78 | APP (0.40) | ALDH1A1APPMAPTL3MBTL1FFAR1 | |
| SCHEMBL8173840 | 0.76 | AKT1 (0.46) | AKT1ALDH1A1LMNAMAPTHPGD | |
| SCHEMBL170296 | 0.69 | ALDH1A1 (0.46) | ALDH1A1APPLMNAMAPTHPGD | |
| SCHEMBL2185852 | 0.68 | AKT1 (0.59) | AKT1ALDH1A1LMNAMAPTHPGD | |
| SCHEMBL8152963 | 0.67 | ALDH1A1 (0.39) | AKT1ALDH1A1APPMAPTL3MBTL1 | |
| SCHEMBL23328518 | 0.66 | AKT1 (0.56) | AKT1ALDH1A1MAPTHPGDL3MBTL1 | |
| SCHEMBL9422531 | 0.66 | AKT1 (0.56) | AKT1ALDH1A1LMNAMAPTHPGD | |
| SCHEMBL313871 | 0.66 | AKT1 (0.56) | AKT1ALDH1A1MAPTHPGDL3MBTL1 | |
| SCHEMBL630088 | 0.66 | AKT1 (0.56) | AKT1ALDH1A1LMNAMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080153019-A1 | ARYLAMINE COMPOUND AND ELECTROPHOTOGRAPHIC PHOTORECEPTOR | FUJIFILM FINECHEMICALS CO., LTD. (JP) | 2008-06-26 | — | — | US | disclosed |
| US-7083863-B2 | Luminous element and method for preparation thereof | MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) | 2006-08-01 | — | — | US | disclosed |
| US-20050194586-A1 | Luminous element and method for preparation thereof | JOLED INC (JP) | 2005-09-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080153019-A1 | ARYLAMINE COMPOUND AND ELECTROPHOTOGRAPHIC PHOTORECEPTOR | NR2E3, ARRB1, ALDH1A2 | AKT1 2474/4885ALDH1A1 165/4885APP 3602/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.