Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 3/20 | 0.37 |
| ▸ | PER2 | O15055 | 8/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.30 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.30 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15468337 | 0.83 | PER2 (0.40) | ACEPER2PIK3CDDPP4DPP8 | |
| SCHEMBL25543646 | 0.76 | CYP1A2 (0.33) | ACE | |
| SCHEMBL15199072 | 0.76 | PER2 (0.35) | PER2PIK3CDDPP4DPP8DPP7 | |
| SCHEMBL7621338 | 0.75 | ACE (0.32) | ACEPER2PIK3CDDPP4DPP8 | |
| SCHEMBL12306282 | 0.75 | PIK3CD (0.55) | PER2PIK3CDDPP4DPP8DPP7 | |
| SCHEMBL19198697 | 0.75 | PIK3CD (0.55) | PER2PIK3CDDPP4DPP8DPP7 | |
| SCHEMBL24449470 | 0.73 | ACE (0.32) | ACE | |
| SCHEMBL12778772 | 0.73 | ACE (0.32) | ACE | |
| SCHEMBL25541942 | 0.72 | PER2 (0.41) | PER2PIK3CDDPP4DPP8DPP7 | |
| SCHEMBL28489524 | 0.72 | ACE (0.40) | ACEPER2PIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150239879-A1 | KETONE LINKED BENZOTHIAZOLE INHIBITORS OF ENDOTHELIAL LIPASE | BRISTOL-MYERS SQUIBB COMPANY | 2015-08-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150239879-A1 | KETONE LINKED BENZOTHIAZOLE INHIBITORS OF ENDOTHELIAL LIPASE | LIPG, LPL, LIPE | ACE 140/4885PER2 4658/4885PIK3CD 1489/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.