Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13234893 | 0.92 | ALDH1A1 (0.35) | ALDH1A1TDP1CYP3A4TSHR | |
| SCHEMBL5961264 | 0.91 | — | — | |
| SCHEMBL14253414 | 0.89 | ALDH1A1 (0.32) | ALDH1A1TDP1CYP3A4TSHR | |
| SCHEMBL12575018 | 0.88 | TSHR (0.35) | ALDH1A1CYP3A4TSHRKDM4E | |
| SCHEMBL18371739 | 0.85 | ALDH1A1 (0.40) | ALDH1A1TDP1CYP3A4TSHRKDM4E | |
| SCHEMBL12657358 | 0.82 | ALDH1A1 (0.31) | ALDH1A1CYP3A4TSHR | |
| SCHEMBL12047862 | 0.81 | ALDH1A1 (0.46) | ALDH1A1TDP1CYP3A4TSHRKDM4E | |
| SCHEMBL26229155 | 0.80 | CA1 (0.39) | KDM4E | |
| SCHEMBL12677246 | 0.78 | ALDH1A1 (0.35) | ALDH1A1TDP1CYP3A4TSHRKDM4E | |
| SCHEMBL26229153 | 0.77 | CACNA2D1 (0.41) | ALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9895315-B2 | Aliphatic amine polymer salts for tableting | GENZYME CORPORATION (US) | 2018-02-20 | — | — | US | disclosed |
| US-20160158275-A1 | PHARMACEUTICAL COMPOSITIONS | GENZYME CORPORATION | 2016-06-09 | — | — | US | disclosed |
| US-20140322319-A1 | PHARMACEUTICAL COMPOSITIONS | GENZYME CORPORATION (US) | 2014-10-30 | — | — | US | disclosed |
| US-8808738-B2 | Aliphatic amine polymer salts for tableting | GENZYME CORPORATION (US) | 2014-08-19 | — | — | US | disclosed |
| US-20120219626-A1 | Pharmaceutical Compositions of Sevelamer | SYNTHON BV (NL) | 2012-08-30 | — | — | US | disclosed |
| US-20120121704-A1 | Aliphatic Amine Polymer Salts for Tableting | GENZYME CORPORATION (US) | 2012-05-17 | — | — | US | disclosed |
| US-20120101234-A1 | PROCESS FOR THE PREPARATION OF SEVELAMER | LABORATORIO CHIMICO INTERNAZIONALE S.P.A. (IT) | 2012-04-26 | — | — | US | disclosed |
| US-20120088886-A1 | PROCESSES FOR THE PREPARATION OF SEVELAMER CARBONATE | Watson Pharma Private Limited (IN) | 2012-04-12 | — | — | US | disclosed |
| US-7985418-B2 | Aliphatic amine polymer salts for tableting | GENZYME CORPORATION (US) | 2011-07-26 | — | — | US | disclosed |
| US-7964182-B2 | Pharmaceutical compositions comprising phosphate-binding polymer | USV, Ltd (IN) | 2011-06-21 | — | — | US | disclosed |
| US-20110081413-A1 | Pharmaceutical Compositions Comprising Phosphate-Binding Polymer | USV LIMITED (IN) | 2011-04-07 | — | — | US | disclosed |
| US-20110064820-A1 | Pharmaceutical Compositions Comprising Phosphate-Binding Polymer | USV PRIVATE LIMITED (IN) | 2011-03-17 | — | — | US | disclosed |
| US-20100331516-A1 | Process for Preparation of Sevelamer Carbonate | USV LTD. (IN) | 2010-12-30 | — | — | US | disclosed |
| US-20090155368-A1 | Pharmaceutical compositions | GENZYME CORPORATION (US) | 2009-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160158275-A1 | PHARMACEUTICAL COMPOSITIONS | SRM, PHPT1, PTH1R | ALDH1A1 2918/4885TDP1 508/4885CYP3A4 3944/4885 |
| US-20120121704-A1 | Aliphatic Amine Polymer Salts for Tableting | ASS1, H1-5, H1-3 | ALDH1A1 2493/4885TDP1 2876/4885CYP3A4 3657/4885 |
| US-20140322319-A1 | PHARMACEUTICAL COMPOSITIONS | SRM, PHPT1, PTH1R | ALDH1A1 2917/4885TDP1 504/4885CYP3A4 3943/4885 |
| US-20110081413-A1 | Pharmaceutical Compositions Comprising Phosphate-Binding Polymer | SLC34A3, SLC34A1, SLC34A2 | ALDH1A1 4734/4885TDP1 2611/4885CYP3A4 2277/4885 |
| US-20110064820-A1 | Pharmaceutical Compositions Comprising Phosphate-Binding Polymer | SLC34A3, SLC34A1, SLC34A2 | ALDH1A1 4734/4885TDP1 2611/4885CYP3A4 2277/4885 |
| US-20120219626-A1 | Pharmaceutical Compositions of Sevelamer | SI, USP47, MGAM | ALDH1A1 1132/4885TDP1 2047/4885CYP3A4 611/4885 |
| US-20090155368-A1 | Pharmaceutical compositions | SRM, PHPT1, PTH1R | ALDH1A1 2918/4885TDP1 508/4885CYP3A4 3944/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.