Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 10/20 | 0.41 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | CNR2 | P34972 | 2/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.36 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16672053 | 0.84 | GPR35 (0.40) | TLR8LIPGMAPTGPR35CYP3A4 | |
| SCHEMBL17037111 | 0.83 | GPR3 (0.39) | LIPGMAPTCNR2CNR1 | |
| SCHEMBL14982706 | 0.82 | SIGMAR1 (0.42) | LIPG | |
| SCHEMBL20730396 | 0.82 | SIGMAR1 (0.42) | LIPG | |
| SCHEMBL15497410 | 0.80 | GPR35 (0.38) | TLR8LIPGMAPTGPR35CYP3A4 | |
| SCHEMBL28046693 | 0.77 | TLR8 (0.61) | TLR8LIPGMAPTCYP3A4 | |
| SCHEMBL9889312 | 0.77 | ALDH1A1 (0.39) | MAPTKDM4EALDH1A1GAAHPGD | |
| SCHEMBL29399266 | 0.77 | ALDH1A1 (0.39) | MAPTKDM4EALDH1A1GAAHPGD | |
| SCHEMBL30257603 | 0.77 | ALDH1A1 (0.39) | MAPTKDM4EALDH1A1GAAHPGD | |
| SCHEMBL16672065 | 0.77 | S1PR1 (0.41) | TLR8KDM4EALDH1A1CYP3A4HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9260451-B2 | Method for producing aromatic compound | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2016-02-16 | — | — | US | disclosed |
| US-20150239901-A1 | Method For Producing Aromatic Compound | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2015-08-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150239901-A1 | Method For Producing Aromatic Compound | TYR, XDH, CYP1A1 | TLR8 4488/4885LIPG 4831/4885MAPT 3301/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.