Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | CES1 | P23141 | 4/20 | 0.46 |
| ▸ | LIG1 | P18858 | 1/20 | 0.46 |
| ▸ | DAO | P14920 | 2/20 | 0.46 |
| ▸ | NSD2 | O96028 | 1/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.39 |
| ▸ | CYP2B6 | P20813 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.37 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | CASP2 | P42575 | 1/20 | 0.37 |
| ▸ | CASP7 | P55210 | 1/20 | 0.37 |
| ▸ | CASP6 | P55212 | 1/20 | 0.37 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 2/20 | 0.36 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17038600 | 0.84 | TGM2 (0.53) | L3MBTL1CES1CYP2A6CYP2B6CYP3A4 | |
| SCHEMBL17038519 | 0.79 | L3MBTL1 (0.55) | L3MBTL1CES1LIG1DAONSD2 | |
| SCHEMBL950588 | 0.73 | CES1 (0.58) | L3MBTL1CES1LIG1DAONSD2 | |
| SCHEMBL2077922 | 0.72 | KEAP1 (0.42) | L3MBTL1CYP2A6CYP2B6CYP3A4CYP2C19 | |
| SCHEMBL281604 | 0.71 | CES1 (0.60) | L3MBTL1CES1LIG1DAONSD2 | |
| SCHEMBL29506270 | 0.71 | CES1 (0.60) | L3MBTL1CES1LIG1DAONSD2 | |
| SCHEMBL17038548 | 0.69 | L3MBTL1 (0.55) | L3MBTL1CES1LIG1DAONSD2 | |
| SCHEMBL31244367 | 0.68 | CES1 (0.60) | L3MBTL1CES1LIG1DAONSD2 | |
| SCHEMBL5332282 | 0.68 | CES1 (0.60) | L3MBTL1CES1LIG1DAONSD2 | |
| SCHEMBL4180952 | 0.67 | CES1 (0.50) | L3MBTL1CES1LIG1DAONSD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015126149-A1 | ISATIN DERIVATIVE AND METHOD FOR PREPARING SAME | 주식회사 대웅제약 | 2015-08-27 | — | — | WO | disclosed |