Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | RAD52 | P43351 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | DGKA | P23743 | 1/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.41 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26626698 | 0.93 | NAAA (0.56) | NAAAALDH1A1RAD52NPSR1DGKA | |
| SCHEMBL28735928 | 0.89 | NAAA (0.35) | NAAAALDH1A1RAD52NPSR1DGKA | |
| SCHEMBL17404783 | 0.88 | TLR2 (0.34) | NAAARAD52NPSR1PRSS1PRSS2 | |
| SCHEMBL16013207 | 0.85 | ALOX5 (0.33) | NAAARAD52NPSR1 | |
| SCHEMBL17411107 | 0.81 | CYP1A2 (0.33) | PRSS1PRSS2PRSS3HTR2C | |
| Ethylene SCHEMBL23781324 | 0.80 | — | — | |
| SCHEMBL25808991 | 0.80 | ALDH1A1 (0.47) | ALDH1A1DGKATSHR | |
| SCHEMBL23781323 | 0.79 | ALDH1A1 (0.34) | ALDH1A1TSHR | |
| SCHEMBL8390835 | 0.78 | ALDH1A1 (0.54) | NAAAALDH1A1RAD52NPSR1ATM | |
| SCHEMBL14682838 | 0.77 | ALDH1A1 (0.35) | NAAAALDH1A1RAD52NPSR1PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015126912-A1 | MARINOPYRROLE DERIVATIVES AND METHODS OF MAKING AND USING SAME | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. (US) | 2015-08-27 | — | — | WO | disclosed |